MAKO 机械臂系统是一项尖端技术，结合了计算机断层扫描 (CT) 扫描和三维规划，可在骨切除之前确定植入物的理想尺寸和方向。它通常用于一般骨科环境中的关节置换手术，例如全关节置换术。然而，其在骨科肿瘤学中的使用，包括更受影响的患者群体和更复杂的手术治疗，在文献中没有得到很好的记录。 确定接受全髋关节置换术 (THA) 或全膝关节置换术的患者的患者结果(TKA) 在莫里斯敦医疗中心使用 MAKO 机械臂系统。特别是，我们渴望深入研究 MAKO 在骨科肿瘤学环境中对患有退行性髋关节或膝关节、有癌症或其他骨科肿瘤病史、即将发生的病理性骨折、PVNS、软骨瘤病、放射治疗或其他肿瘤相关病史的患者的使用。我们的机构对 25 名患有独特骨科肿瘤疾病的患者进行了监测，这些患者接受了 MAKO 机器人辅助的全髋关节和膝关节置换术。该研究于 2020 年至 2022 年在新泽西州莫里斯敦医疗中心进行。在此期间，52% (13/25) 的手术在膝盖上进行，48% (12/25) 在臀部进行。有关患者人口统计数据、体重指数 (BMI)、药物、血红蛋白、血细胞比容、合并症、美国麻醉医师协会 (ASA) 等级、手术数据、住院时间 (LOS)、因感染或假体周围骨折导致的再入院率的数据，以及回顾性收集并发症。所有置信区间均按 95% 置信水平计算。术后，平均 LOS 为 3.2 天，任何 MAKO 辅助关节置换术均未出现并发症。此外，在我们记录的任何时间间隔（1-30 年、1-60 年、1-90 年和 1 年）中都没有再入院的情况，但一名患者在术后 4 天跌倒后被送往急诊室。 X 射线成像最终显示没有假体周围骨折或假体错位。使用 MAKO 机械臂系统对骨科肿瘤患者进行关节置换术（THA 和 TKA）取得了优异的结果，没有直接归因于并发症或再入院的情况。使用这种创新的机器人技术。因此，这种新兴的手术系统具有巨大的前景，与传统的手工技术相比，可能会彻底改变特定骨科肿瘤患者接受全关节置换术的方法。它进一步表明，它在骨科肿瘤学环境中的使用（患者群经常受到损害，导致更复杂的手术和更高的风险）可以带来安全性并为患者提供最佳结果。尽管如此，它在该领域的作用正在不断发展，在未来几年，随着它进一步普及并得到骨肿瘤外科医生的更广泛应用，其潜力将变得更加清晰。为了巩固其地位，应进行未来的临床调查和前瞻性研究，以支持 MAKO 系统相对于传统手工技术的偏好。这将有助于提供必要的证据来倡导其在骨科肿瘤学手术中的广泛采用和持续进步。© 2023 P K Surendran 教授纪念教育基金会。由 Elsevier B.V. 出版。保留所有权利。

The MAKO Robotic-Arm system is a cutting-edge technology which combines both computed tomography (CT) scanning and three-dimensional planning to determine the ideal size and orientation of implants prior to bone resection. It is typically utilized within a general orthopedic setting for joint replacement procedures, such as total joint arthroplasties. However, its use within orthopedic oncology, which contains a much more compromised patient population and more complex surgical treatment, is not well documented within the literature.To determine the patient outcomes of those who underwent a total hip arthroplasty (THA) or total knee arthroplasty (TKA) at Morristown Medical Center using the MAKO Robotic-Arm System. Particularly, we aspired to delve into the use of the MAKO in an orthopedic oncology setting for patients with a degenerative hip or knee and a history of cancer or other orthopedic tumor, impending pathological fracture, PVNS, chondromatosis, radiation therapy, or other oncological related conditions.Our institution monitored twenty-five individuals with unique orthopedic oncology conditions that underwent MAKO robotic-assisted total hip and knee arthroplasty. This was performed between 2020 and 2022 at Morristown Medical Center in New Jersey. During this time period, 52% (13/25) of the operations were performed on knees and 48% (12/25) were performed on hips. Data regarding patient demographics, body mass index (BMI), medications, hemoglobin, hematocrit, comorbidities, American Society of Anesthesiologists (ASA) Class, operative data, the length of stay (LOS), readmission rates due to infection or periprosthetic fractures, and complications were collected retrospectively. All confidence intervals were calculated at the 95% confidence level.Postoperatively, the average LOS was 3.2 days, and there were no complications after any of the MAKO-assisted joint arthroplasty procedures. Additionally, there were no readmissions at any of our recorded intervals - 1-30, 1-60, 1-90, and 1 year - however one patient presented to the emergency department after falling 4 days post-operatively. X-ray imaging ultimately revealed no periprosthetic fracture or malalignment of the prosthesis.The utilization of the MAKO Robotic-Arm System for joint arthroplasty procedures (THAs and TKAs) on orthopedic oncology patients yielded exceptional outcomes, with no complications or readmissions directly attributed to the use of this innovative robotic technology. Thus, this newly emerging surgical system holds great promise, potentially revolutionizing the approach for selected orthopedic oncology patients undergoing total joint arthroplasty compared to the traditional manual techniques. It further demonstrates that its use in an orthopedic oncology setting - where the cohort of patients are often compromised, leading to more intricate surgeries with heightened risks - elicits safety and provides optimal outcomes for patients. Nevertheless, its role within the field is evolving, and in the coming years, as it gains further popularity and sees broader application by orthopedic oncology surgeons, its potential will become clearer. To solidify its position, future clinical investigations and prospective research should be conducted to support the preference of the MAKO system over traditional manual techniques. This will help provide the necessary evidence to advocate for its widespread adoption and continued advancements in orthopedic oncology procedures.© 2023 Professor P K Surendran Memorial Education Foundation. Published by Elsevier B.V. All rights reserved.