回顾对儿科髓母细胞瘤认识的最新进展，包括儿科髓母细胞瘤的病因学、生物学、放射学和治疗。经典的四个亚组已根据新的分子发现重新分类并进一步细分。研究揭示了髓母细胞瘤不同亚型的细胞起源。基于分子参数的管理持续个性化。虽然这种最常见的恶性儿童脑肿瘤的知识库已经取得了许多进展，但尚未转化为更有效的疗法来延长所有亚组的生存期，但患有第 3 组疾病的儿童可能除外。生活质量仍然是长期幸存者的一项重大挑战。© 2023。作者。

Review recent advances in the understanding of pediatric medulloblastoma including etiology, biology, radiology, and management of pediatric medulloblastoma.The classic four subgroups have been reclassified and further subdivided based on new molecular findings. Research is revealing the cell origins of the different subtypes of medulloblastoma. There has been continued personalization of management based on molecular parameters. While many advances have been made in the knowledge base of this most common malignant pediatric brain tumor, there has not yet been translation into more effective therapies to prolong survival in all subgroups with the possible exception of children with group 3 disease. Quality of life remains a major challenge for long-term survivors.© 2023. The Author(s).