镰刀菌属是患有不相关疾病的患者中的机会性真菌病原体。墨西哥有关人类镰刀菌感染的数据很少。在这里，我们回顾性地介绍了在墨西哥八家不同医院确诊为镰刀菌病的患者的一系列情况。已证实的镰刀菌病的诊断是根据欧洲癌症研究和治疗组织以及真菌病研究组教育和研究联盟 (EORT/MSG) 标准进行的。我们的系列中发现了 49 个病例。大多数患者患有烧伤（49%），37%患有血液恶性肿瘤。大多数患者有火伤（40%），其次是电伤（8%）、发热性中性粒细胞减少症（10%）和全血细胞减少症（6%）。 48% 的患者有皮肤和软组织受累，随后进行了血培养分离和身体不同部位（肺、鼻窦、骨组织、眼睛）的活检。大多数患者接受伏立康唑作为单一药物治疗（30%），然后接受两性霉素 B 脂质制剂（20%）或传统两性霉素 B（16%）。最常见的联合疗法是三唑加两性霉素 B 脂质制剂 (30%)。 22% 的患者发生与镰刀菌感染相关的死亡。镰刀菌病是一个严重的威胁。在墨西哥的这个小型系列文章中，烧伤和血液恶性肿瘤是最常见的感染原因。© 作者 2023。由牛津大学出版社代表国际人类和动物真菌学学会出版。

Fusarium species represent an opportunistic fungal pathogen in patients with an unrelated disease. The data in Mexico about Fusarium infections in humans are scarce. Here, we present a retrospective series of patients with a confirmed diagnosis of fusariosis in eight different hospitals in Mexico. The diagnosis of proven fusariosis was made according to European Organization for Research and Treatment of Cancer and the Mycoses Study Group Education and Research Consortium (EORT/MSG) criteria. Forty-nine cases were identified in our series. Most patients had burn injuries (49%) and 37% had hematological malignancy. Most patients had fire injuries (40%), followed by electric injury (8%), febrile neutropenia (10%), and pancytopenia (6%). Patients had skin and soft tissue involvement in 48%, followed by blood culture isolation and biopsies from different sites of the body (lung, sinuses, bone tissue, eyes). Most patients received voriconazole as a single drug therapy (30%), followed by a lipidic formulation of amphotericin B (20%) or conventional amphotericin B (16%). The most common combination therapy was triazole plus a lipidic formulation of amphotericin B (30%). Mortality related to Fusarium infection occurred in 22% of patients. Fusariosis is a serious threat. Burn injuries and hematologic malignancies represent the most common causes of infection in this small series from Mexico.© The Author(s) 2023. Published by Oxford University Press on behalf of The International Society for Human and Animal Mycology.