辅酶Q10（CoQ10），俗称泛醌，是线粒体内膜中产生的维生素样成分。这种分子在人体的不同部位广泛检测到，数量各异。这种分子可以作为补充剂被消化系统从各种营养来源吸收。 CoQ10以三种状态存在：还原形式（泛醇）、半醌自由基形式和氧化泛醌形式，在身体不同器官中发挥着至关重要的作用，在电子运输中发挥着至关重要的作用，有助于能量代谢和氧气利用，特别是在肌肉骨骼和神经系统中。自 20 世纪 80 年代初以来，关于 CoQ10 的研究引起了人们的兴趣，原因有二。首先，CoQ10 缺乏已被发现与心血管、神经系统和癌症疾病有关。其次，该分子具有抗氧化剂和自由基清除剂的性质。此后，多项研究表明该药物可能有益于患有心血管、神经肌肉和神经退行性疾病的患者。由于其在线粒体中的抗氧化和能量调节活性，辅酶 Q10 可以保护神经系统免受变性和降解。该药物在预防和治疗偏头痛、帕金森病、阿尔茨海默病、亨廷顿病、肌萎缩侧索硬化症和弗里德赖希共济失调等神经系统疾病方面已显示出功效。本研究回顾了文献，以强调该药物对上述神经系统疾病的潜在治疗效果。版权所有 © 2023 Alireza Ebrahimi 等人。

Coenzyme Q10 (CoQ10), commonly known as ubiquinone, is a vitamin-like component generated in mitochondrial inner membranes. This molecule is detected broadly in different parts of the human body in various quantities. This molecule can be absorbed by the digestive system from various nutritional sources as supplements. CoQ10 exists in three states: in a of reduced form (ubiquinol), in a semiquinone radical form, and in oxidized ubiquinone form in different organs of the body, playing a crucial role in electron transportation and contributing to energy metabolism and oxygen utilization, especially in the musculoskeletal and nervous systems. Since the early 1980s, research about CoQ10 has become the interest for two reasons. First, CoQ10 deficiency has been found to have a link with cardiovascular, neurologic, and cancer disorders. Second, this molecule has an antioxidant and free-radical scavenger nature. Since then, several investigations have indicated that the drug may benefit patients with cardiovascular, neuromuscular, and neurodegenerative illnesses. CoQ10 may protect the neurological system from degeneration and degradation due to its antioxidant and energy-regulating activity in mitochondria. This agent has shown its efficacy in preventing and treating neurological diseases such as migraine, Parkinson's disease, Alzheimer's disease, Huntington's disease, amyotrophic lateral sclerosis, and Friedreich's ataxia. This study reviews the literature to highlight this agent's potential therapeutic effects in the mentioned neurological disorders.Copyright © 2023 Alireza Ebrahimi et al.