作者开发了一款疼痛监测应用程序，为癌症儿童提供教育信息以及有关临床显着疼痛（>4 数字评分量表 [NRS]-11）的实时医疗保健专业反馈，以减轻家庭疼痛。这个单中心、非盲随机研究对照试验招募了接受癌症治疗的荷兰儿童（0-18 岁）（诊断后≥3 个月，剩余治疗时间≥2 个月）。儿童被随机分配使用该应用程序或接受常规护理（两个平行组）。我们评估了该应用程序的使用是否会减少临床上显着的疼痛（目标 1），以及它是否会影响疼痛的严重程度、持续时间、干扰、疼痛管理策略和父母的情绪健康（目标 2）。该应用程序还接受了家庭的评估（目标 3）。共有 94 名儿童被随机分配使用该应用程序（15 名中途退出），90 名儿童将照常接受护理（11 名中途退出）。与常规护理（n = 79，平均年龄：7.5 [5.4]）相比，应用组（n = 79，平均年龄：7.5 [5.1] 岁，48% 女孩，63% 血液肿瘤诊断）报告的临床显着疼痛明显减轻年，52% 女孩，65% 血液肿瘤诊断）（比值比 [OR]，0.38；95% 置信区间 [CI]，0.198-0.734]）（目标 1），以及显着降低疼痛严重程度 (β = -0.27；95% CI，-0.407 至 -0.142）。在持续时间、干扰或管理策略方面没有发现差异。与常规护理相比，应用程序组的家长报告的痛苦显着减少（β = -0.84；95% CI，-1.61 至 -0.03]）（目标 2）。家庭普遍对该应用程序给予积极评价（目标 3）。使用该应用程序可以减轻家庭中临床上显着的疼痛。该应用程序的确切工作机制应进一步阐明。© 2023 美国癌症协会。

The authors developed a pain monitoring app offering educational information, and real-time health care professional feedback on clinically significant pain (>4 numeric rating scale [NRS]-11) for children with cancer to reduce pain at home.This monocenter, nonblinded randomized controlled trial enrolled Dutch children (0-18 years old) receiving cancer treatment (≥3 months after diagnosis, ≥2 months treatment remaining). Children were randomly assigned to use the app or receive usual care (two parallel groups). We assessed whether use of the app yielded less clinically significant pain (aim 1) and whether it affected pain severity, duration, interference, pain management strategies, and parental emotional well-being (aim 2). The app was also evaluated by families (aim 3).A total of 94 children were randomized to use the app (15 drop-outs), and 90 were to receive care as usual (11 drop-outs). The app group (n = 79, mean age: 7.5 [5.1] years, 48% girls, 63% hemato-oncology diagnosis) reported significantly less clinically significant pain compared to usual care (n = 79, mean age: 7.5 [5.4] years, 52% girls, 65% hemato-oncology diagnosis) (odds ratio [OR], 0.38; 95% confidence interval [CI], 0.198-0.734]) (aim 1), as well as significantly lower pain severity (β = -0.27; 95% CI, -0.407 to -0.142). No differences were found for duration, interference, or management strategies. Parents in the app group reported significantly less distress compared to usual care (β = -0.84; 95% CI, -1.61 to -0.03]) (aim 2). Families generally evaluated the app positively (aim 3).Use of the app resulted in less clinically significant pain at home. The exact working mechanisms of the app should be further elucidated.© 2023 American Cancer Society.