切除边缘的状态是口腔舌癌手术切除完整性的指标，因此是术后预后的有用预测指标。从历史上看，5 毫米或更大的边缘距离被认为是负边缘，并且被认为在控制和生存方面会带来好处。为了更完整地总结有关该主题的文献，我们进行了系统综述，检查了口腔舌癌的径向边缘距离及其与疾病控制和生存的关系。我们的综述包括 34 项研究，这些研究根据切缘状态报告了口腔舌癌患者的生存和/或复发结果。大多数研究报告了 5 毫米边缘的结果，而少数研究则使用了其他边缘截止值。对于 5 毫米截止值，生存和复发结果总体上是有利的。尽管如此，使用 4 毫米、3.3 毫米和 10 毫米截止值的研究也发现了良好的生存和复发结果；然而，这些只是纳入研究的一小部分。版权所有 © 2023 Elsevier Ltd。保留所有权利。

The status of resection margins is a proxy for the completeness of resection in oral tongue cancer surgery and is therefore a useful predictor for post-operative prognosis. Historically, a margin distance of 5 mm or greater has been deemed a negative margin and is believed to yield a benefit in terms of control and survival. To summarize the literature more completely on this topic, we conducted a systematic review that examines radial margin distance and its relationship to disease control and survival in oral tongue cancer. Our review includes 34 studies which reported survival and/or recurrence outcomes for oral tongue cancer patients based on margin status. Most studies reported outcomes for the 5 mm margin, while the minority utilized other margin cutoffs. For the 5 mm cutoff, outcomes were generally favorable regarding survival and recurrence outcomes. Nonetheless, studies using 4 mm, 3.3 mm, and 10 mm cutoffs also found favorable survival and recurrence outcomes; however, these are a minority of the included studies.Copyright © 2023 Elsevier Ltd. All rights reserved.