刺参Meyer:植物学、植物化学、药理学、药代动力学和认证的全面综述。
Panax japonicus C.A. Meyer: a comprehensive review on botany, phytochemistry, pharmacology, pharmacokinetics and authentication.
发表日期:2023 Nov 10
作者:
Yuan Chen, Meiqi Liu, Jinli Wen, Zijie Yang, Guohui Li, Ying Cao, Lili Sun, Xiaoliang Ren
来源:
ANTIOXIDANTS & REDOX SIGNALING
摘要:
刺参美尔(助结神)在中国、日本和韩国作为滋补止血消炎剂广泛用于传统医学。此外,它被中国少数民族用作人参根的重要替代品。本文旨在对近年来珠结神的研究进展进行综述,旨在对珠结神的研究现状进行系统的概述,并对未来的研究和开发进行展望。逐节参的药代动力学及验证.已报道多种化合物作为活性成分,主要包括皂苷、挥发油和多糖。药理研究表明,珠结神是一种重要的中药材,具有抗炎、保肝、心脏、神经保护、抗肿瘤、抗氧化、抗血栓、免疫调节等显着的生物活性。逐节神研究尚处于初步阶段,需要进一步研究以了解其活性化合物的存在和作用机制。我们希望对诸界神的全面回顾能够作为未来研究和开发的背景。© 2023。作者。
Panax japonicus C.A. Meyer (Zhujieshen) is widely used in traditional medicine as a tonic hemostatic and anti-inflammatory agent in China, Japan, and Korea. Furthermore, it is used as an important substitute for ginseng roots by minority ethnic groups in China. The purpose of this review is to summarize the latest research on Zhujieshen in recent years, aiming at providing a systematic overview of the current knowledge, and perspectives for future research and exploitation.This review examines the research advances in botanical profile, phytochemicals, pharmacology, pharmacokinetics, and authentication of Zhujieshen. Various compounds have been reported as active components, mainly including saponins, volatile oils, and polysaccharides. Pharmacological investigations have demonstrated that Zhujieshen is an important herb with significant bioactivities, such as anti-inflammatory, hepato-protective, cardio-protective, neuro-protective, anti-tumor, anti-oxidant, anti-thrombotic and immunomodulatory activities.Currently, research on Zhujieshen is in the preliminary stages, and further research is required to understand the active compounds present and mechanisms of action. We hope that this comprehensive review of Zhujieshen will serve as a background for future research and exploitation.© 2023. The Author(s).