需要制定预防计划来帮助成年人改善饮食质量，以降低癌症风险。这项 IIa 期研究前瞻性地测试了一项移动健康干预措施，旨在提高对癌症预防膳食质量指南的遵守率。所有参与者 (N = 62) 都接受了营养教育和自我调节技能课程，主要目标是改变杂货购物行为。该研究采用随机、因子设计，改变了是否将以下 4 个组成部分添加到 20 周的干预中：(1) 位置触发的应用程序消息传递，当个人到达杂货店时发送，(2) 对改变，通过额外的辅导时间和定制的应用程序消息来传递，(3) 教练监控，其中由教练对食品购买进行数字监控，以及 (4) 家庭成员参与干预。成功达到了招聘、保留的基准和治疗的可接受性。在不同条件下，高度加工食品的摄入量（P < .001，η2 = .48）、红肉和加工肉类的摄入量（P < .001，η2 = .20）以及含糖饮料的摄入量（P = .20）均显着减少。 .008, η2 = .13) 从处理前到处理后。检查每个干预措施是否影响随时间变化的分析发现，接受教练监控的参与者增加了水果、蔬菜和纤维的摄入量，而没有接受教练监控的参与者改善较小（P = .01，η2 = .14）。与家庭支持关闭的参与者相比，家庭支持开启的参与者在红肉和加工肉类方面的改善更强，处于边际显着水平（P = .056，η2 = .07）。这项研究显示了可行性、可接受性和初步信号远程干预的有效性，以促进遵守癌症预防饮食指南，并且教练监测和家庭支持可能是特别有效的策略。需要进行全面的临床试验来测试干预措施的优化版本，其中包括营养教育、自我调节技能培训、教练监控和家庭成员参与。ClinicalTrials.gov NCT04947150。

Prevention programs that can help adults improve the quality of their diets to reduce cancer risk are needed. This Phase IIa study prospectively tested a mHealth intervention designed to improve adherence to dietary quality guidelines for cancer prevention.All participants (N = 62) received nutrition education and a self-regulation skills curriculum, with a primary target of changing grocery shopping behavior. Using a randomized, factorial design, the study varied whether each of the following 4 components were added to the 20-week intervention: (1) location-triggered app messaging, delivered when individuals arrived at grocery stores, (2) reflections on benefits of change, delivered with extra coaching time and tailored app messages, (3) coach monitoring, in which food purchases were digitally monitored by a coach, and (4) involvement of a household member in the intervention.Benchmarks were successfully met for recruitment, retention, and treatment acceptability. Across conditions, there were significant reductions in highly processed food intake (P < .001, η2 = .48), red and processed meat intake (P < .001, η2 = .20), and sugar-sweetened beverage intake (P = .008, η2 = .13) from pre-to post-treatment. Analyses examining whether each intervention component influenced change across time found that participants who received coach monitoring increased their intake of fruits, vegetables, and fiber, whereas those with no coach monitoring had less improvement (P = .01, η2 = .14). The improvement in red and processed meat was stronger among participants with household support ON, at a marginally significant level, than those with household support OFF (P = .056, η2 = .07).This study showed feasibility, acceptability, and preliminary signals of efficacy of a remotely delivered intervention to facilitate adherence to dietary guidelines for cancer prevention and that coach monitoring and household support may be especially effective strategies. A fully powered clinical trial is warranted to test an optimized version of the intervention that includes nutrition education, self-regulation skills training, coach monitoring, and household member involvement.ClinicalTrials.gov NCT04947150.