介绍我们接受简单子宫颈切除术的早期宫颈癌患者的病例系列。目前，根治性宫颈切除术被认为是治疗早期宫颈癌最合适的保留生育能力的手术。然而，为了保护肿瘤安全，关于手术的适当激进性的争论越来越多。对患者记录的描述性回顾性分析和问卷评估设置：两个妇科肿瘤中心，由一个手术团队进行手术患者：36 名患有早期肿瘤的女性接受单纯子宫颈切除术的阶段宫颈癌 干预措施：腹腔镜辅助单纯阴道子宫颈切除术 测量：对 2007 年 4 月至 2021 年 7 月期间接受单纯子宫颈切除术的所有患者的人口学、组织学、生育力和随访数据进行前瞻性记录和回顾性分析。36 名女性（平均年龄：28 岁）接受了单纯子宫颈切除术，其中 81% 为未产妇。单纯子宫颈切除术的适应症分别为多灶性FIGO IA1期（n=30）、IA1 L1期（n=1）、IA2期（n=2）和IB1期（n=3）。强制性分期程序是腹腔镜盆腔淋巴结切除术，其中 92% 的病例进行双侧前哨活检，8% 的病例进行系统性活检。 8 个标本（22%）经组织学证实有残留肿瘤。 18 名女性 (50%) 正在寻求生育，其中 13 名成功 (72%)。共有 16 名活产婴儿，全部足月，胎儿中位体重为 3110（2330-4420）克。一名患者因胎儿先天畸形而进行药物流产。一名怀孕正在进行中。中位随访时间为 91.5 (9-174) 个月后，所有女性均存活，没有任何疾病证据。与根治性子宫颈切除术相比，简单子宫颈切除术代表了降级，并为患者提供了出色的肿瘤学结果、出色的生育率和产科结局患有早期宫颈癌。然而，这种量身定制的生育力保留手术的明确适应症必须在精心设计的试验中确定。版权所有 © 2023。由 Elsevier Inc. 出版。

to present our case series of patients with early-stage cervical cancer undergoing simple trachelectomy. Currently, radical trachelectomy is considered the most appropriate fertility preserving procedure for the treatment of early-stage cervical cancer. However, there is increasing debate on the appropriate radicality of the surgery in order to preserve oncologic safety.descriptive retrospective analysis of patient records and evaluation of questionaires SETTING: two gynecologic oncologic centers, surgeries performed by one surgical team PATIENTS: 36 women with early-stage cervical cancer undergoing simple trachelectomy INTERVENTIONS: laparoscopic assisted simple vaginal trachelectomy MEASUREMENTS: Demographic, histological, fertility and follow-up data of all patients who underwent simple trachelectomy between 04/2007 and 7/2021 were prospectively recorded and retrospectively analyzed.36 women (mean age: 28 years) underwent simple trachelectomy of whom 81% were nulliparous. Indications for simple trachelectomy were multifocal FIGO stage IA1 (n=30), stage IA1 L1 (n=1), stage IA2 (n=2) and stage IB1 (n=3), respectively. Mandatory staging-procedure was laparoscopic pelvic lymphadenectomy, including bilateral sentinel-biopsy in 92% of the cases and systematic in 8%. Residual tumor was histologically confirmed in 8 specimens (22%). 18 women (50%) were seeking parenthood, 13 succeeded (72%). There were 16 live births, all on term, with a median fetal weight of 3110 (2330-4420) gram. One patient had a medical abortion due to fetal congenital malformation. One pregnancy is ongoing. After a median follow-up of 91.5 (9-174) months all women are alive with no evidence of disease.Simple trachelectomy represents a de-escalation compared to radical trachelectomy and provides excellent oncologic results with an outstanding fertility rate and obstetrical outcome for patients with early cervical cancer. However, clear indications for this tailored fertility-preserving surgery have to be defined in well-designed trials.Copyright © 2023. Published by Elsevier Inc.