慢性复发性多灶性骨髓炎 (CRMO) 是一种影响骨骼系统的自身炎症性疾病，但尚未得到充分认识。其模糊症状通常首先归因于生长痛、感染或恶性肿瘤，这可能导致诊断延迟数天至数年。未经治疗的 CRMO 有可能导致骨骼畸形、关节炎和慢性疼痛；因此早期识别和治疗至关重要。 MRI 是诊断的金标准。治疗包括各种抗炎药物，如果涉及脆弱的骨骼部位，还可能包括双磷酸盐。即使接受治疗，该疾病也可能会出现持续数年的复发病程。版权所有 © 2023 Elsevier Inc. 保留所有权利。

Chronic recurrent multifocal osteomyelitis (CRMO) is an underrecognized autoinflammatory disease affecting the skeletal system. Its vague symptoms are often first attributed to growing pains, infection, or malignancy, which can lead to a delay in diagnosis for days to years. Untreated CRMO has the potential to cause debilitating skeletal deformities, arthritis, and chronic pain; hence early recognition and treatment are paramount. MRI is the gold standard for diagnosis. Treatment consists of various antiinflammatory medications and may also include bisphosphonates if vulnerable skeletal sites are involved. Even when treated, the disease may have a relapsing course lasting years.Copyright © 2023 Elsevier Inc. All rights reserved.