携带人类免疫缺陷病毒的人患上艾滋病定义的恶性肿瘤（包括伯基特淋巴瘤）的风险增加。尽管广泛实施抗逆转录病毒治疗，但艾滋病毒相关伯基特淋巴瘤的生存结果仍然比非艾滋病毒相关伯基特淋巴瘤差。我们的目的是确定美国因伯基特淋巴瘤住院后 HIV 状况与 30 天和 90 天再入院风险之间的关联。数据摘自 2010-2020 年全国再入院数据库；住院治疗包括初步 BL 诊断的患者，并按合并症 HIV 进行分层。主要结局是全因再入院（30 天和 90 天）。次要结局是院内死亡率、住院时间 (LOS) 和住院费用。通过逻辑回归和对数正态回归评估艾滋病毒之间的差异；针对共病肾脏疾病、高血压、液体和电解质紊乱以及败血症进行了多变量模型调整。总体而言，有 8,453 人因 BL 住院，其中 6.0% 被诊断为 HIV。在 BL 住院治疗中，68.4% 的人在 BL 住院后 30 天内再次入院，6.8% 的人被诊断为 HIV。 HIV 相关 BL 与 30 天再入院的调整后几率升高 43% 相关（aOR 95% CI：升高 4% 至 97%，p = 0.026）。在 90 天的再入院中，76.0% 的 BL 患者再次入院，7.0% 的患者被诊断为 HIV。 HIV 相关 BL 与全因 90 天再入院没有统计学相关性（aOR 1.46，aOR 95% CI：高出 0% 至 115%，p = 0.053）。 HIV 阳性状态与 30 天内的风险增加相关。因伯基特淋巴瘤住院后 - 天再次入院。© 2023。作者。

People with human immunodeficiency virus have an increased risk of developing AIDS-defining malignancies including Burkitt lymphoma. Survival outcomes in HIV-associated Burkitt lymphoma remain worse than non-HIV-associated Burkitt lymphoma, despite widespread implementation of antiretroviral therapy. We aimed to determine the association between HIV status and risk for 30-day and 90-day readmission in the US after index hospitalization for Burkitt lymphoma.Data were abstracted from the 2010-2020 Nationwide Readmissions Database; hospitalizations included patients with a primary BL diagnosis and were stratified by comorbid HIV. The primary outcome was all-cause readmission (30-day and 90-day). Secondary outcomes were in-hospital mortality, length of stay (LOS), and hospital cost. Between-HIV differences were evaluated via logistic and log-normal regression; multivariable models adjusted for comorbid kidney disease, hypertension, fluid and electrolyte disorders, and sepsis.Overall, there were 8,453 hospitalizations for BL and 6.0% carried an HIV diagnosis. Of BL hospitalizations, 68.4% were readmitted within 30-days post index BL hospitalization and 6.8% carried a HIV diagnosis. HIV-associated BL was associated with 43% higher adjusted odds of 30-day readmission (aOR 95% CI: 4% higher to 97% higher, p = 0.026). For 90-day readmission, 76.0% of BL patients were readmitted and 7.0% carried a HIV diagnosis. HIV-associated BL was not statistically associated with all-cause 90-day readmission (aOR 1.46, aOR 95% CI: 0% higher to 115% higher, p = 0.053).HIV-positive status is associated with an increased risk for 30-day readmission after index hospitalization for Burkitt lymphoma.© 2023. The Author(s).