硒（Se）因其对人体具有抗癌、抗炎、抗氧化活性而被科学界称为“长寿元素”。硒的地球化学性质和生物功能已在地质学、农业和医学等各个领域得到广泛研究。巴马瑶族自治县（巴马）是中国人口寿命高的典型乡镇，被选为研究区。本研究有机结合地质背景、膳食结构、吸收代谢等生物地球化学方面，综合分析高硒条件下硒和富含纤维多糖膳食的抗衰老特性。系统采集环境和居民表层土壤、食物、头发、尿液等生物地球化学样品，分析硒的含量和形态。巴马土壤中硒浓度为中高浓度，高硒土壤占77.21%。水溶性硒浓度也较高，90%的样品中含有中高硒，且与农作物中硒浓度呈显着正相关。研究区的膳食样品具有较高的总硒含量和高有效硒含量，显示出富硒的特征。相应地，人群硒摄入量也较高（82.54μg/d），有力地维持了老年人的正常身体机能。根据60岁以上居民头发和尿液中硒的浓度评估人群硒的积累和代谢。研究发现硒的持续积累发生在71岁至80岁之间。 71岁以下和80岁以上居民硒浓度处于损失状态。总体而言，硒的吸收和代谢保持在最佳的生理状态，是维持研究区老年人健康长寿的首要因素之一。版权所有©2023。由Elsevier Ltd.出版。

Selenium (Se) has been called the "longevity element" by the scientific community because it has anti-cancer, anti-inflammatory, and anti-oxidant activity in humans. The geochemical properties and biological functions of Se have been widely studied in various fields, including geology, agriculture, and medicine. Bama Yao Autonomous County (Bama), a typical township in China with high longevity among the population, was selected as the research area. The present study organically combines the geological background, dietary structure, absorption and metabolism, and other biogeochemical aspects to comprehensively analyze the anti-aging properties of Se under high-Se conditions and a fiber-rich polysaccharide diet. Biogeochemical samples of surface soil, food, human hair, and urine were systematically collected from the environment and the residents, and the content and speciation of Se were analyzed. Concentrations of Se in the soil were moderate to high for Bama, with high-Se soil in 77.21% of the samples. Water-soluble Se concentrations were also high, 90% of the samples with moderate to high Se, and had a significant positive correlation with Se concentrations in crops. With both high total and high available Se, dietary samples from the study area showed Se-enriched characteristics. Accordingly, Se intake was also high (82.54 μg/d) in the population, strongly maintaining the normal bodily functions of the elderly. Accumulation and metabolism of Se in the population were assessed based on concentrations of Se in the hair and urine of residents over 60 years old. Continuous accumulation of Se was found to occur from 71 to 80 years of age. Concentrations of Se in residents under 71 years old and over 80 years old were in a state of loss. Overall, Se absorption and metabolism are maintained at the optimal physiological state, which is one of the primary factors maintaining the health and longevity of the elderly people in the study area.Copyright © 2023. Published by Elsevier Ltd.