目的 探讨动态对比增强（DCE）磁共振成像（MRI）结合常规MRI定量参数对泪腺上皮性良恶性鉴别诊断的价值。回顾性分析经组织病理学证实的原发性泪腺上皮性肿瘤进行了。收集常规MRI特征和DCE-MRI定量参数并进行分析。采用受试者工作特征（ROC）曲线分析评估诊断价值。共纳入53例患者，其中29例为恶性肿瘤，24例为良性肿瘤。常规 MRI 显示良性肿瘤和恶性肿瘤在最大肿瘤直径、后缘特征、骨破坏和侵蚀方面存在统计学显着差异。 DCE-MRI获得的Ktrans和Kep值在恶性肿瘤中高于良性肿瘤，且具有统计学意义（p<0.001和p=0.022）。 I 型时间信号强度 (TIC) 曲线在良性肿瘤中更为常见，而 II 型 TIC 曲线在恶性肿瘤中更为常见 (p=0.001)。 ROC分析显示Ktrans在DCE-MRI参数中具有最佳诊断价值（ROC曲线下面积[AUC]为0.822，敏感性为75.9%，特异性为83.3%，p<0.001）。常规MRI和DCE-MRI因素的组合具有最佳的诊断价值，且敏感性和特异性均衡（AUC为0.948，敏感性为93.1%，特异性为91.7%，p<0.001）。目前的研究结果表明，定量参数的组合DCE-MRI 和常规 MRI 的图像特征对于良恶性泪腺上皮肿瘤的诊断具有较高的诊断价值。版权所有 © 2023。由 Elsevier Ltd 出版。

To establish the diagnostic value of the quantitative parameters of dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) combined with conventional MRI in differentiating of benign and malignant lacrimal gland epithelial tumours.A retrospective analysis of primary lacrimal gland epithelial tumours confirmed by histopathology was conducted. Conventional MRI features and DCE-MRI quantitative parameters were collected and subjected to analysis. The diagnostic value was evaluated using receiver operating characteristic (ROC) curve analysis.A total of 53 patients were enrolled of which 29 had malignant, whereas 24 had benign tumours. Conventional MRI revealed statistically significant differences between benign and malignant tumours regarding maximum tumour diameter, posterior margin characteristic, bone destruction, and erosion. The Ktrans and Kep values obtained by DCE-MRI were higher in malignant than in benign tumours, with a statistically significant (p<0.001 and p=0.022). A type I time-signal intensity (TIC) curve was more frequent in benign tumours, whereas a type II TIC curve was prevalent in malignant tumours (p=0.001). ROC analysis showed that Ktrans had the best diagnostic value of the DCE-MRI parameters (area under the ROC curve [AUC] of 0.822, 75.9% sensitivity, and 83.3% specificity, p<0.001). The combination of conventional MRI and DCE-MRI factors had the best diagnostic value and balanced sensitivity and specificity (AUC of 0.948, 93.1% sensitivity, and 91.7% specificity, p<0.001).The present findings indicate that the combination of quantitative parameters of DCE-MRI and image characteristics of conventional MRI have a high diagnostic value for the diagnosis of benign and malignant lacrimal gland epithelial tumours.Copyright © 2023. Published by Elsevier Ltd.