铊-201 单光子发射计算机断层扫描/计算机断层扫描 (SPECT/CT) 脑部扫描是一种成像方式，可用于区分传统神经影像学未得出结论的患者的恶性和非恶性病变。本研究描述了铊 201 SPECT/CT 脑成像的结果，并将其与组织病理学和/或临床发现联系起来，并评估铊 201 SPECT/CT 脑成像在区分恶性与非恶性病变中的价值。这是一个回顾性病例系列一项研究对2010年至2021年在菲律宾一家医院接受铊201 SPECT/CT脑部成像的10名脑部病变患者进行了研究。共有10名患者接受了铊201 SPECT/CT脑部扫描。 6 例呈阴性结果，4 例呈阳性结果。所有呈阳性结果的患者均被发现患有恶性肿瘤，无论是复发的还是新诊断的。所有扫描呈阴性的患者都被发现患有传染性和炎症性疾病，并且对治疗有不同程度的反应。 10例患者中有2例接受了活检，其结果与铊201 SPECT/CT脑部扫描结果一致。铊201脑部扫描结合SPECT和SPECT/CT已被证明有助于区分恶性与非恶性病变，并且更有效。与其他成像技术相比具有成本效益。这项研究的结果支持铊闪烁扫描在脑部病变患者的诊断中的作用，当需要区分恶性和良性病变时，其作用最为显着。版权所有 © 2023 韩国脑肿瘤协会、韩国神经肿瘤学会肿瘤学和韩国儿科神经肿瘤学会。

Thallium-201 single-photon emission computed tomography/computed tomography (SPECT/CT) brain scan is an imaging modality which can be done to differentiate between malignant and nonmalignant lesions among patients with nonconclusive findings on conventional neuroimaging. This study describes the results of thallium-201 SPECT/CT brain imaging and relate it to histopathologic and/or clinical findings and evaluate the value of thallium-201 SPECT/CT brain imaging in differentiating malignant from nonmalignant lesions.This is a retrospective case series study of 10 patients with cerebral lesions who underwent thallium-201 SPECT/CT brain imaging in a hospital in the Philippines from 2010 to 2021.A total of 10 patients underwent thallium-201 SPECT/CT brain scan. Six had negative results while 4 had positive results. All of the patients who had positive results were found to have malignancy, whether recurrent or newly diagnosed. All of the patients with negative scan were found to have either an infectious and inflammatory disease and responded to treatment albeit in different degrees. Two of the 10 patients underwent biopsy whose results were consistent with the thallium-201 SPECT/CT brain scan results.Thallium-201 brain scan combined with SPECT and SPECT/CT has been demonstrated to be useful in distinguishing malignant from nonmalignant lesions and is more cost-effective versus other imaging techniques. The findings in this study support the role of thallium scintigraphy in the diagnosis of patients with brain lesions most significantly when there is a need to differentiate between a malignant and benign condition.Copyright © 2023 The Korean Brain Tumor Society, The Korean Society for Neuro-Oncology, and The Korean Society for Pediatric Neuro-Oncology.