人类 BLT2 的两种不同形式:长型 BLT2 和短型 BLT2。
Two distinct forms of human BLT2: long-form and short-form BLT2.
发表日期:2023
作者:
Jun-Dong Wei, Jae-Hong Kim
来源:
Frontiers in Cell and Developmental Biology
摘要:
BLT2 是一种低亲和力白三烯 B4 受体,在多种炎症性疾病(包括哮喘和癌症)的发病机制中发挥重要作用。 BLT2 在正常内部环境中表达最低,但在应激诱导的炎症环境中过度表达。最近的研究表明人类 BLT2 有两种不同的形式。尽管它们的功能可能不同,但很少有研究调查这些差异。因此,本文将讨论人类 BLT2 的两种不同形式; BLT2 的缩写形式和 BLT2 的长形式。版权所有 © 2023 Wei 和 Kim。
BLT2 is a low-affinity leukotriene B4 receptor that plays an essential role in the pathogenesis of various inflammatory diseases, including asthma and cancer. BLT2 is minimally expressed in a normal internal environment but is overexpressed in a stress-induced inflammatory environment. Recent research indicated that human BLT2 has two distinct forms. Although their functions are likely to be different, very few studies investigated these differences. Therefore, this paper will discuss about the two distinct forms of human BLT2; the short-form of BLT2 and the long-form of BLT2.Copyright © 2023 Wei and Kim.