金银花藤活性代谢产物及药理作用研究进展综述
Lonicerae Japonicae Caulis: a review of its research progress of active metabolites and pharmacological effects.
发表日期:2023
作者:
Yu-Xia Cao, Peng Ji, Fan-Lin Wu, Jia-Qi Dong, Chen-Chen Li, Ting Ma, Hao-Chi Yang, Yan-Ming Wei, Yong-Li Hua
来源:
Frontiers in Pharmacology
摘要:
金银花茎为忍冬科植物忍冬的地上茎部分,在我国属于药食同源种。具有清热解毒、疏风通络的功效。现代研究表明,其含有多种活性代谢物和广泛的药理作用,具有重大的研究和临床应用价值。主要含有有机酸、挥发油、黄酮类、三萜类、三萜皂苷等活性代谢物。其药理作用主要包括抗炎、抗菌、抗肿瘤、抗氧化、修复骨和软组织等。依据近年来文献报道,对金银花藤的活性代谢产物、药理作用及作用机制进行了整理和总结。为阐明金银花藤的功效物质基础和应用价值奠定了基础。旨在为金银花藤的深入研究、开发利用提供参考。版权所有©2023曹、吉、吴、董、李、马、杨、韦、华。
Lonicerae Japonicae Caulis is the aboveground stem part of the Lonicera Japonica Thunb, which belongs to the medicine food homology species in China. It has the effects of clearing away heat, toxic material, dredging wind and unblocking collaterals. Modern research shows that it contains various active metabolites and a wide range of pharmacological effects, which is of great research and clinical application value. It mainly contains organic acids, volatile oils, flavonoids, triterpenes, triterpene saponins and other active metabolites. Its pharmacological effects mainly include anti-inflammatory, antibacterial, antitumor, antioxidant, and repairing bone and soft tissue. Based on the literature reports in recent years, the active metabolites, pharmacological effects and mechanisms of Lonicerae Japonicae Caulis were sorted out and summarized. It lays a foundation for explaining the efficacy material basis and application value of Lonicerae Japonicae Caulis. It aims to provide a reference for the in-depth research, development and utilization of Lonicerae Japonicae Caulis.Copyright © 2023 Cao, Ji, Wu, Dong, Li, Ma, Yang, Wei and Hua.