背景：独脚金内酯是植物产生的信号分子，主要功能是体内控制植物发育和植物生长。 GR24独脚金内酯是合成独脚金内酯之一，由于其通用性和易得性，它是研究独脚金内酯的性质和对人类健康的作用的标准和模型化合物。目的：在这项研究工作中，主要回顾了GR24独脚金内酯对人体的影响以及这种独脚金内酯在人体内发生的许多过程中的作用。研究设计：本文是对 2010-2023 年研究中 GR24 独脚金内酯使用的出版物的回顾。使用 PubMed、Elsevier、Frontiers 和 Springer 数据库检索出版物。还使用了谷歌学术搜索引擎。为了进行审查，选择了与所提出的主题相关的原始研究论文和评论。结果：GR24 和其他独脚金内酯类似物在抗癌治疗中具有良好的前景。肿瘤的发展与血管生成的增加有关。独脚金内酯已被证明可以抑制血管生成，这可能会增强这些 γ-内酯的抗癌作用。此外，研究表明独脚金内酯具有抗炎和抗氧化特性。还有一些报告表明独脚金内酯类似物可能对人类病原体具有抗菌和抗病毒活性。结论：考虑到所有这些因素，独脚金内酯分子的多功能性是其不可否认的优势。对这些植物激素的研究进展使得我们有可能发现它们与许多哺乳动物细胞相关的新的、独特的特性和令人惊讶的生物活性。版权所有 © 2023 Pyrzanowska-Banasiak、Boyunegmez Tumer、Bukowska 和 Krokosz。

Background: Strigolactones are signaling molecules produced by plants, the main functions are the intracorporeal control of plant development and plant growth. GR24 strigolactone is one of the synthetic strigolactones and due to its universality and easy availability, it is a standard and model compound for research on the properties and role of strigolactones in human health. Purpose: In this research work, the impact of mainly GR24 strigolactone on the human body and the role of this strigol-type lactone in many processes that take place within the human body are reviewed. Study design: The article is a review of publications on the use of GR24 strigolactone in studies from 2010-2023. Publications were searched using PubMed, Elsevier, Frontiers, and Springer databases. The Google Scholar search engine was also used. For the review original research papers and reviews related to the presented topic were selected. Results: The promising properties of GR24 and other strigolactone analogs in anti-cancer therapy are presented. Tumor development is associated with increased angiogenesis. Strigolactones have been shown to inhibit angiogenesis, which may enhance the anticancer effect of these γ-lactones. Furthermore, it has been shown that strigolactones have anti-inflammatory and antioxidant properties. There are also a few reports which show that the strigolactone analog may have antimicrobial and antiviral activity against human pathogens. Conclusion: When all of this is considered, strigolactones are molecules whose versatile action is their undeniable advantage. The development of research on these phytohormones makes it possible to discover their new, unique properties and surprising biological activities in relation to many mammalian cells.Copyright © 2023 Pyrzanowska-Banasiak, Boyunegmez Tumer, Bukowska and Krokosz.