地方性高山茶(Sideritis dichotoma Huter):抗氧化和抗菌活性、ICP-MS 测定的矿物质含量和 LCHR-MS 测定的植物化学成分。
Endemic Mountain Tea (Sideritis dichotoma Huter): Antioxidant and Antibacterial Activities, Mineral Content by ICP-MS and Phytochemical Content by LCHR-MS.
发表日期:2023 Nov 13
作者:
S Beyza Ozturk Sarikaya, Cuma Zehiroglu
来源:
ANTIOXIDANTS & REDOX SIGNALING
摘要:
地方性黄萁炎 花草茶,用于治疗感冒、咳嗽和消化系统疾病。由于至少 25% 的药理药物活性成分是从植物中获得的,因此在许多传统使用的植物和尚未发现其潜力的植物消失之前对其进行研究非常重要。结果与其他Sideritis品种相比,其在DPPH•清除活性、Fe3和Cu2还原能力方面具有更好的抗氧化活性,并且还富含人体必需的矿物质、K、Mg、Ca、P、S区值。在金黄色葡萄球菌、铜绿假单胞菌、大肠杆菌、肠炎沙门氏菌、粪肠球菌、恶臭假单胞菌和肺炎克雷伯菌菌株上获得的 (10-19,5 mm) 表明该植物具有抗菌活性。通过 LC-HRMS 鉴定出 27 种次生代谢物。毛蕊花苷是已知具有抗肿瘤作用、细胞毒性选择性和抗癌活性的药理活性化合物,是乙醇提取物中最丰富的酚类物质 (49297.13 mg/kg)。© 2023 Wiley-VCH GmbH。
Endemic Sideritis dichotoma Huter, herbal tea, is used for colds, coughs and digestive ailments. Since at least 25% of the active ingredients of pharmacological drugs are obtained from plants, it is important to investigate many plants, both traditionally used and whose potential hasnt yet been discovered, before they disappear. When the results compared to other Sideritis species, it has better antioxidant activity in DPPH• scavenging activity, Fe3+ and Cu2+ reducing capacity methods and is also rich in minerals, necessary for human body, K, Mg, Ca, P, S. Zone values (10-19,5 mm) obtained on S. aureus, P. aeruginosa, E. coli, S.enteritidis, E. faecalis, P. putida and K. pnemoniae strains are an indication that the plant has antibacterial activity. 27 secondary metabolites were identified by LC-HRMS. Verbascoside, pharmacologically active compound known to have antitumor effect, cytotoxic selectivity and anticancer activity, is the most abundant phenolic in ethanol extract (49297.13 mg/kg).© 2023 Wiley-VCH GmbH.