一只 50 岁的雌性赫曼陆龟 (Testudo hermannii boettgeri) 出现厌食和嗜睡症状。临床检查发现壳内有多个视觉上不显眼但有凹痕的区域，对应于放射学上的骨溶解。四肢也发现软组织结节和溶骨性病变。实验室结果显示天冬氨酸转氨酶活性和尿酸浓度升高、低血糖和高磷血症。从活检的盾片区域分离出产酸克雷伯氏菌，活检提示肿瘤形成。经过短暂的临床改善后，动物的病情恶化并死亡。死后计算机断层扫描显示多块骨头和甲壳的多骨性溶解性病变，相关软组织结节伸入体腔，以及结节性肺部病变。尸检、组织病理学和免疫组织化学诊断为低分化、全细胞角蛋白阳性鳞状细胞癌，伴有广泛的软组织和骨转移、骨质溶解和结缔组织增生。Thieme。版权所有。

A 50-year-old female Hermann's tortoise (Testudo hermannii boettgeri) was presented with anorexia and lethargy. Clinical examination revealed multiple, visually inconspicuous but indentable areas in the shell corresponding to osteolysis radiographically. Soft tissue nodules and osteolytic lesions were also noted in the limbs. Laboratory results revealed elevated aspartate aminotransferase activity and uric acid concentrations, hypoglycemia, and hyperphosphatemia. Klebsiella oxytoca was isolated from a biopsied scutal area, and the biopsy suggested neoplasia. After a short period of clinical improvement, the animal's condition deteriorated, and it died. Post mortem computed tomography revealed polyostotic lytic lesions of multiple bones and the shell with associated soft tissue nodules protruding into the coelom, and nodular lung lesions. Necropsy, histopathology, and immunohistochemistry secured a diagnosis of a poorly differentiated, pan-cytokeratin-positive squamous cell carcinoma with widespread soft tissue and bone metastases, osteolysis and desmoplasia.Thieme. All rights reserved.