乳腺癌因其在全球范围内的高发病率而受到全球关注，更值得注意的是，大约90%的乳腺癌死亡归因于癌症转移。因此，乳腺癌转移的早期诊断对于降低死亡率具有重要意义。生物传感器由于其易用性、便携性和实时分析能力等优点，在转移性乳腺癌的早期检测中发挥着至关重要的作用。本综述主要描述了基于生物标志物和细胞特征检测乳腺癌转移的各种类型的传感器，包括电化学、光学和微流控芯片。我们详细描述了这些不同生物传感器的性能，并对它们进行了比较。此外，我们描述了乳腺癌的病理学并总结了转移性乳腺癌的常用生物标志物。最后，我们讨论了现阶段生物传感器的优势和需要解决的挑战，以及其未来的发展前景。

Breast cancer has garnered global attention due to its high incidence worldwide, and even more noteworthy is that approximately 90% deaths due to breast cancer are attributed to cancer metastasis. Therefore, the early diagnosis of breast cancer metastasis holds significant importance for reducing mortality outcomes. Biosensors play a crucial role in the early detection of metastatic breast cancer due to their advantages, such as ease of use, portability, and real-time analysis capabilities. This review primarily described various types of sensors for detecting breast cancer metastasis based on biomarkers and cell characteristics, including electrochemical, optical, and microfluidic chips. We offered detailed descriptions of the performance of these various biosensors and made comparisons between them. Furthermore, we described the pathology of breast cancer and summarized commonly used biomarkers for metastatic breast cancer. Finally, we discussed the advantages of current-stage biosensors and the challenges that need to be addressed, as well as prospects for their future development.