早期何杰金氏病的大多数患者现在可以通过几种治疗方法中的一种来治愈。该综述强调了诊断和治疗该疾病的发展，这些发展已经使得长期存活率高达90%以上。根据临床和病理分期，讨论了过去和现在的放射治疗（RT）规划和治疗实践。回顾了初始双模治疗（RT和化疗[CT]）的作用以及在初始仅使用RT治疗后出现复发的患者中使用CT的情况。基于预后因素，现在已经确定了接受双模治疗的患者亚组，包括那些患有巨大纵隔肿块的患者。虽然治疗非常成功，但放射治疗和化学治疗等副作用，如不育症、感染和第二恶性疾病等仍然存在。新的治疗方案可能会减少发病率，并且在生存和生活质量方面有类似或更好的长期结果。

Most patients with early-stage Hodgkin's disease can now be cured by one of several therapeutic approaches. This review highlights the developments in the diagnosis and treatment of the disease that have led to long-term survival rates greater than 90%. Past and present radio-therapy (RT) planning and treatment practices are discussed in the context of both clinical and pathological staging. The role of initial bimodal therapy (RT and chemotherapy [CT]) and the use of CT in patients who suffer relapse after initial treatment with RT alone are reviewed. On the basis of prognostic factors, subgroups of patients for whom bimodal therapy is recommended, including those with a bulky mediastinal mass, have now been identified. Although treatment is highly successful, debilitating consequences of RT and CT, such as infertility, infection and second malignant diseases, remain. Newer treatment regimens may reduce morbidity and have similar or better long-term results with respect to survival and quality of life.