恶性高热 (MH) 是一种可能危及生命的药物遗传学综合征，由挥发性麻醉剂、琥珀胆碱和剧烈运动等压力引发。作者描述了一名 8 岁男性的病例，该男孩在诱导恶性高热后出现了典型的 MH 症状。由于无法获得丹曲林，全身麻醉和对症治疗得以成功完成。MH 的明确诊断可以基于新鲜肌肉活检中氟烷和咖啡因存在下的挛缩测试来进行。在没有肌肉活检和基因检测的情况下，可以根据 MH 评分来诊断 MH。麻醉科医生应该意识到，适当的症状管理也可以挽救患者的生命。此外，应大力宣传，确保丹曲林的可用性，并进一步加强实验室设施以确认诊断，以方便未来的诊断和管理。版权所有 © 2024 作者。由 Wolters Kluwer Health, Inc. 出版

Malignant hyperthermia (MH) is a potentially life-threatening pharmacogenetic syndrome triggered by volatile anaesthetics, succinylcholine, and stress such as vigorous exercise.The authors describe a case of an 8-year-old male who presented with classical symptoms of MH after induction of general anaesthesia and symptomatic treatment was done successfully due to the unavailability of Dantrolene.Definitive diagnosis of MH can be done based on a contracture test in fresh muscle biopsy in the presence of halothane and caffeine. In the absence of muscle biopsy and genetic testing, diagnosis for MH can be done based on MH scoring.Anesthesiologists should be made aware that proper symptomatic management can also save the life of a patient. Also, strong advocacy should be done to ensure the availability of Dantrolene and further strengthen lab facilities to confirm diagnosis to facilitate diagnosis and management in the future.Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc.