中药前胡(Peucedanum decursivum)的干燥根，历史上治疗咳嗽、痰稠、头痛、发热等呼吸系统疾病，以及妇科疾病、类风湿性关节炎、鼻咽癌等。通过PubMed、Web of Science、CNKI等数据库对1955年至2024年的文献和书籍进行了细致的检索，包括“P. decursivum”的主题和关键词。 ”《当归》和《紫花千户》.P.地草及其方剂传统上用于治疗痰热咳嗽、风热咳嗽、胃肠疾病、止痛等。它含有 234 种已鉴定的化合物，包括香豆素、萜烯、挥发油、酚酸、脂肪酸及其衍生物。它具有多种药理活性，包括抗哮喘、抗炎、抗氧化作用、抗高血压、抗糖尿病、抗阿尔茨海默病和抗癌特性，主要归因于香豆素。显微鉴定、HPLC指纹图谱、生物信息学鉴定是目前质量控制的主要方法。 decursivum 具有抗哮喘、抗炎和抗氧化作用，与其传统用途相符。然而，需要通过实验验证其对抗痰和病毒的功效。此外，历史文献中提到的镇痛作用缺乏现代药理学研究。许多分离的化合物表现出非常有价值的药用特性。未来的研究可以进一步深入探索这些物质。严格控制重金属污染，特别是镉和铅的污染是必要的。同时，研究其在人体中的药代动力学和毒性对于安全性至关重要。版权所有 © 2024。由 Elsevier B.V. 出版。

Dried roots of Peucedanum decursivum, a traditional Chinese medicine (TCM), has historically respiratory diseases such as cough, thick phlegm, headache, fever, and gynecological diseases, rheumatoid arthritis, and nasopharyngeal carcinoma.Made an endeavor to evaluate the research trajectory of P. decursivum, comprehensively discern its developmental status, and offer a guideline for future investigations.A meticulous search of literatures and books from 1955 to 2024 via databases like PubMed, Web of Science and CNKI was conducted, including topics and keywords of " P. decursivum" "Angelica decursivum" and "Zihua Qianhu".P. decursivum and its prescriptions have traditionally been used for treating phlegm-heat cough, wind-heat cough, gastrointestinal diseases, pain relief and so on. It contains 234 identified compounds, encompassing coumarins, terpenes, volatile oils, phenolic acids, fatty acids and derivatives. It exhibits diverse pharmacological activities, including anti-asthmatic, anti-inflammatory, antioxidant effects, anti-hypertensive, anti-diabetic, anti-Alzheimer, and anti-cancer properties, primarily attributed to coumarins. Microscopic identification, HPLC fingerprinting, and bioinformatics identification are the primary methods currently used for the quality control.P. decursivum demonstrates anti-asthmatic, anti-inflammatory, and antioxidant effects, aligning with its traditional use. However, experimental validation of its efficacy against phlegm and viruses is needed. Additionally, analgesic effects mentioned in historical texts lack modern pharmacological studies. Numerous isolated compounds exhibit highly valuable medicinal properties. Future research can delve into exploring these substances further. Rigorous of heavy metal contamination, particularly Cd and Pb, is necessary. Simultaneously, investigating its pharmacokinetics and toxicity in humans is crucial for the safety.Copyright © 2024. Published by Elsevier B.V.