提供人乳头瘤病毒 (HPV) 疫苗可有效消除 HPV 相关癌症的差异。自2016年疫苗获得许可并批准使用以来，中国HPV疫苗接种分布的不平等情况尚不清楚。本研究旨在探讨HPV相关知识和疫苗接种方面的社会经济不平等，并找出与这种不平等相关的因素。通过在线调查平台，1306名女性完成了HPV相关知识和疫苗接种情况调查问卷。 HPV 知识使用 12 项问题进行评估，涵盖 HPV 感染的危害、HPV 疫苗剂量、益处和保护。通过结合家庭月收入、教育水平和就业状况进行聚类分析来确定社会经济地位（SES）类别。集中指数（CI）被用来衡量 HPV 相关知识和疫苗接种方面的社会经济不平等。建立线性回归和逻辑回归来分解相关因素对观察到的不平等的贡献。HPV相关知识和疫苗接种的CI分别为0.0442和0.1485，表明较高的知识和疫苗接种率集中在高SES群体中。教育和家庭收入对这些不平等的影响最大。年龄、居住地和宫颈癌筛查也是造成不平等的重要因素。HPV 相关知识和疫苗接种情况的社会经济不平等在中国很明显。向弱势群体传播 HPV 相关信息的干预措施有助于减少这些不平等。提供低成本或免费 HPV 疫苗接种并确保农村地区疫苗的可及性也被认为是有益的。版权所有 © 2024 龚、徐、何、邹和刘。

Providing the human papillomavirus (HPV) vaccine is effective to eliminate the disparity in HPV-related cancers. It is unknown regarding inequality in the distribution of HPV vaccination in China since the vaccine was licensed and approved for use in 2016. This study aimed to examine socioeconomic inequalities in HPV-related knowledge and vaccination and identified factors associated with such inequalities.Self-administered questionnaires measuring HPV-related knowledge and vaccine uptake were completed by 1,306 women through online survey platform. HPV knowledge was assessed using a 12-item question stem that covered the hazards of HPV infection, HPV vaccine dosage, benefits, and protection. Cluster analysis by combining monthly household income, educational level, and employment status was used to identify socioeconomic status (SES) class. The concentration index (CI) was employed as a measure of socioeconomic inequalities in HPV-related knowledge and vaccination. Linear regression and logistic regression were established to decompose the contributions of associated factors to the observed inequalities.The CI for HPV-related knowledge and vaccine uptake was 0.0442 and 0.1485, respectively, indicating the higher knowledge and vaccination rate were concentrated in groups with high SES. Education and household income made the largest contribution to these inequalities. Age, residency and cervical cancer screening were also important contributors of observed inequalities.Socioeconomic inequalities in HPV-related knowledge and vaccination uptake are evident in China. Interventions to diffuse HPV-related information for disadvantaged groups are helpful to reduce these inequalities. Providing low or no-cost HPV vaccination and ensuring accessibility of vaccines in rural areas are also considered to be beneficial.Copyright © 2024 Gong, Xu, He, Zou and Liu.