患者报告的结果测量（PROM）对于评估皮肤癌治疗的价值和更好地比较治疗方案是必要的。开发和验证牛津皮肤癌治疗（OxSCanTr）量表，评估与健康相关的生活质量和皮肤癌治疗后的满意度癌症治疗。经过定性患者访谈、国际专家咨询和项目缩减后，使用 2 个独立的患者样本来评估量表的因子结构。使用分类变量和多向相关矩阵进行探索性因子分析，然后进行 promax 倾斜旋转，以建立 A 组的因子结构。使用 Satorra-Bentler 标度检验统计量进行验证性因子分析，评估近似均方根误差 (RMSEA)，对 B 组进行标准化残差均方根 (SRMR) 和比较拟合指数 (CFI)。使用 McDonald omega 评估作为内部一致性的可靠性。使用 Pearson 相关系数评估收敛效度和判别效度。共有 480 名受试者返回了已完成的调查（完成率 96%）。制定了包含 4 个领域的 12 项量表：审美满意度、治疗选择满意度、治疗体验以及未来对复发/扩散的担忧。验证性因子分析显示出出色的拟合优度特征，使用 4 因子模型时 RMSEA = 0.048、SRMR = 0.051 和 CFI = 0.962。可靠性非常好（麦当劳 omega 0.81-0.82），FACE-Q 皮肤癌模块疤痕子量表评估的收敛效度也非常好（r = 0.55）。关于保守的单个问题的判别效度同样出色 (r = -0.02)。OxSCanTr 量表是一种简约、可行且有效的 PROM，用于对接受过皮肤癌治疗的患者的经历进行整体评估。版权所有 © 2024由美国皮肤外科学会出版。由 Wolters Kluwer Health, Inc. 出版。保留所有权利。

Patient-reported outcome measures (PROMs) are necessary to assess the value of skin cancer treatment and to better compare therapeutic options.To develop and validate the Oxford Skin Cancer Treatment (OxSCanTr) scale, evaluating health-related quality of life and satisfaction after skin cancer treatment.After qualitative patient interviews, international expert consultation, and item reduction, 2 separate patient samples were used to assess the factor structure of the scale. Exploratory factor analysis with categorical variables and a polychoric correlation matrix followed by promax oblique rotation was performed to establish a factor structure on Group A. Confirmatory factor analysis with a Satorra-Bentler scaled test statistic evaluating the root mean squared error of approximation (RMSEA), standardized root mean squared residual (SRMR), and comparative fit index (CFI) was conducted on Group B. Reliability as internal consistency was assessed using McDonald omega. Convergent and discriminant validity were assessed using the Pearson correlation coefficient.A total of 480 subjects returned completed surveys (completion rate 96%). A 12-item scale was developed encompassing 4 domains: aesthetic satisfaction, treatment choice satisfaction, treatment experience, and future concerns regarding recurrence/spread. Confirmatory factor analysis showed excellent goodness-of-fit characteristics, with RMSEA = 0.048, SRMR = 0.051, and CFI = 0.962 using the 4-factor model. Reliability was very good (McDonald omega 0.81-0.82), as was convergent validity with the FACE-Q skin cancer module appraisal of scars subscale (r = 0.55). Discriminant validity with a single question regarding being conservative was similarly excellent (r = -0.02).The OxSCanTr scale is a parsimonious, feasible, and valid PROM for the holistic assessment of the experience of patients who have undergone skin cancer treatment.Copyright © 2024 by the American Society for Dermatologic Surgery, Inc. Published by Wolters Kluwer Health, Inc. All rights reserved.