节俭的组织更喜欢回收的嘌呤而不是新的嘌呤。
Thrifty tissues prefer recycled purines over new-cleotides.
发表日期：2024 Jul 11
作者：
David Sokolov, Lucas B Sullivan
来源：
MOLECULAR CELL
摘要：
在《Cell1》和《细胞代谢》杂志上发表的两项最新研究中，2 Tran 等人。和吴等人。描述了有机体和细胞嘌呤核苷酸补救途径中未被充分认识的细微差别，并将嘌呤补救确定为肿瘤生长的代谢限制。版权所有 © 2024 Elsevier Inc. 保留所有权利。
In two recent studies appearing in Cell1 and Cell Metabolism,2 Tran et al. and Wu et al. describe underappreciated nuance in organismal and cellular purine nucleotide salvage pathways and identify purine salvage as a metabolic limitation for tumor growth.Copyright © 2024 Elsevier Inc. All rights reserved.