人们对直肠癌患者如何做出治疗选择知之甚少，并且可能会影响长期的遗憾和满意度。本研究的目的是描述接受直肠癌恢复性直肠切除术的患者的决策偏好及其对决策后悔的影响。一项前瞻性队列研究于 2018 年 10 月至 2022 年 6 月在单一学术专科直肠癌中心进行。 成年患者招募至少一年前接受过恢复性直肠切除术的人。使用BRIEF 工具评估健康素养。使用控制偏好量表评估有关癌症治疗的决策偏好。使用决策后悔评分评估他们选择恢复性直肠切除术的决策后悔。使用低前切除综合征评分来测量肠功能障碍。总共包括 123 名患者。 63% 的人健康素养为充足，25% 的人健康素养为勉强，12% 的人健康素养有限。与健康素养较低的患者相比，具有足够健康素养的患者更有可能更喜欢协作决策角色（86% vs 65%，P = .016）。首选角色与实际决策角色不一致的患者更有可能表示高度后悔（56% vs 25%，P = .003）。与无/轻微低位前切除综合征的患者相比，患有严重低位前切除综合征的患者也更有可能经历高度后悔（44% vs 25%，P = 0.036）。很大比例的直肠癌患者接受恢复性直肠切除术没有符合其偏好的决策角色，这些患者会感到高度遗憾。版权所有 © 2024。由 Elsevier Inc. 出版。

How patients make treatment choices in rectal cancer is poorly understood and may affect long-term regret and satisfaction. The objective of this study is to characterize decision-making preferences and their effect on decisional regret in patients undergoing restorative proctectomy for rectal cancer.A prospective cohort study was conducted in a single academic specialist rectal cancer center from October 2018 to June 2022. Adult patients who underwent restorative proctectomy at least one year prior were recruited. Health literacy was assessed using the BRIEF instrument. Decision-making preferences regarding cancer treatment were assessed using the Control Preferences Scale. Decisional regret regarding their choice of restorative proctectomy was assessed using the Decision Regret Score. Bowel dysfunction was measured using the low anterior resection syndrome score.Overall, 123 patients were included. Health literacy was categorized as adequate in 63%, marginal in 25%, and limited in 12%. Patients with adequate health literacy were more likely to prefer a collaborative decision-making role compared with those with low health literacy (86% vs 65%, P = .016). Patients with incongruence between preferred and actual decision-making roles were more likely to report high regret (56% vs 25%, P = .003). Patients with major low anterior resection syndrome were also more likely to experience high regret compared with patients with no/minor low anterior resection syndrome (44% vs 25%, P = .036).A significant proportion of patients with rectal cancer undergoing restorative proctectomy do not have a decision-making role that is congruent with their preferences, and these patients experience a high degree of regret.Copyright © 2024. Published by Elsevier Inc.