本研究旨在探讨单次卧推 (BP) 与腿举 (LP) 阻力训练对睾酮、皮质醇、C 反应蛋白 (CRP) 白介素 6 (IL-6)、肿瘤坏死因子的影响接受过力量训练的男性的 α (TNF-α) 浓度和肌酸激酶 (CK) 活性。 11 名接受过力量训练的男性参加了一项交叉随机试验，进行了两次实验，每次包括五组 BP 或 LP 练习，直至意志力衰竭，负荷相当于一次重复最大次数的 50%。在基线 (BA)、运动后立即 (POST) 和运动停止后 1 小时 (POST-1) 采集血样。在 LP 条件下观察到从 BA 到 POST-1，IL-6 浓度显着增加（p = 0.004；效应大小 [ES] = 0.64）。此外，还发现时间对从 BA 到 POST 运动期间睾酮浓度的增加有显着的主效应（p = 0.014；ES = 0.25）。在 BP 条件下，与 POST 相比，POST-1 时的皮质醇浓度显着降低（p = 0.001；ES = 1.02）。此外，与 LP 条件相比，在 POST-1 时发现 BP 的皮质醇浓度显着降低（p = 0.022；ES = 1.3）。据报道，在 LP 条件下，从 BA 到 POST（p = 0.024；ES = 0.69）和 POST-1（p = 0.045；ES = 0.55）以及从 BA 到 POST-1（p = 0.014）CK 活性显着增加; ES = 0.96) 在 BP 条件下。 CRP (p = 0.659) 和 TNF-α 浓度 (p = 0.487) 没有发现显着差异。这些结果表明，抗阻运动期间参与的肌肉量可能会影响 IL-6 和皮质醇浓度的变化。参与 LP 的肌肉群越大，更有可能导致 IL-6 肌因子浓度升高。

This study aimed to investigate the effects of a single bench press (BP) vs. leg press (LP) resistance training sessions on testosterone, cortisol, C-reactive protein (CRP) interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α) concentrations, and creatine kinase (CK) activity in strength-trained males. Eleven strength-trained males participated in a cross-over randomized trial, undergoing two experimental sessions each consisting of five sets of the BP or the LP exercise to volitional failure with a load corresponding to 50% of one-repetition maximum. Blood samples were taken at baseline (BA), immediately post (POST), and 1 h after the cessation of exercise (POST-1). A significant increase in IL-6 concentration from BA to POST-1 was observed during the LP condition (p = 0.004; effect size [ES] = 0.64). Additionally, a significant main effect of time was found for increasing testosterone concentrations from BA to POST exercise (p = 0.014; ES = 0.25). A significantly lower cortisol concentration at POST-1 compared to POST (p = 0.001; ES = 1.02) was noted in the BP condition. Furthermore, a significantly lower cortisol concentration was found at POST-1 in the BP compared to the LP condition (p = 0.022; ES = 1.3). A significant increase in CK activity was reported from BA to POST (p = 0.024; ES = 0.69) and POST-1 (p = 0.045; ES = 0.55) during the LP condition, and from BA to POST-1 (p = 0.014; ES = 0.96) during the BP condition. No significant differences were found in the CRP (p = 0.659) and TNF-α concentrations (p = 0.487). These results suggest that the amount of muscle mass engaged during the resistance exercise may influence the changes in IL-6 and cortisol concentrations. Larger muscle groups, as engaged in the LP, more likely lead to elevated concentrations of IL-6 myokine.