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肿瘤

急性髓系白血病

肾上腺皮质癌

膀胱尿路上皮癌

对极早期乳腺癌（≤30岁）患者的遗传检测发现大量胚系致病变异，主要集中在BRCA1、TP53和BRCA2基因

Genetic Testing of Breast Cancer Patients with Very Early-Onset Breast Cancer (≤30 Years) Yields a High Rate of Germline Pathogenic Variants, Mainly in the BRCA1, TP53, and BRCA2 Genes

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Cancers

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发表日期:2024 Jun 27

作者:

DOI:10.3390/cancers16132368

摘要

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对极早期乳腺癌（≤30岁）患者的遗传检测发现大量胚系致病变异，主要集中在BRCA1、TP53和BRCA2基因

Genetic Testing of Breast Cancer Patients with Very Early-Onset Breast Cancer (≤30 Years) Yields a High Rate of Germline Pathogenic Variants, Mainly in the BRCA1, TP53, and BRCA2 Genes

摘要

Abstract