慢性粒细胞白血病（CML）是一种累及骨髓和淋巴系统的恶性增殖性疾病。视网膜受累是 CML 患者的一种罕见表现形式。我们报告了一名 49 岁女性的病例，她出现急性双侧视力障碍。她的双眼最初视力为 20/20。眼底检查发现多处淡黄色视网膜浸润、血管鞘和周围血管硬化。眼底荧光素血管造影显示双侧周边视网膜缺血。黄斑光学相干断层扫描显示，视网膜内层和外层以及视网膜下腔内分布着不同大小的高反射病变。全身检查显示明显的白细胞增多，骨髓活检显示 CML。 CML 患者很少出现眼部症状。早期识别和及时转诊对于挽救生命至关重要。版权所有：© 2024 中东非洲眼科杂志。

Chronic myeloid leukemia (CML) is a malignant proliferative disorder involving the bone marrow and lymphatic system. Retinal involvement is a rare form of presentation in patients with CML. We report a case of a 49-year-old woman who presented with an acute bilateral visual disturbance. Her initial visual acuity was 20/20 in both eyes. Fundus examination revealed multiple yellowish retinal infiltrates, vascular sheathing, and peripheral sclerosed blood vessels. Fundus fluorescein angiography revealed bilateral peripheral retinal ischemia. Optical coherence tomography of the macula showed varying sizes of hyperreflective lesions distributed within the inner and outer retinal layers and in the subretinal space. Systemic workup revealed marked leukocytosis, and bone marrow biopsy revealed CML. Patients with CML can rarely present with ocular symptoms. Early recognition and prompt referral are crucial in lifesaving.Copyright: © 2024 Middle East African Journal of Ophthalmology.