心血管疾病（CVD）涉及心脏和血管功能障碍，已成为全世界的主要健康问题。 CVD的发生、发展可能涉及多种机制。尽管心血管疾病的治疗方法不断被开发和应用，但心血管疾病的发病率和死亡率仍然很高。人们正在探索天然化合物在CVD治疗中的作用，为CVD的治疗提供新的方法。五环三萜是具有 30 个碳原子基本核的天然化合物，因其在治疗 CVD 方面的潜在应用而被广泛研究，其多种药理活性有助于包括抗炎、抗氧化和抗肿瘤作用。本综述介绍了三萜类化合物在预防和治疗 CVD 中的作用，总结了其潜在的潜在机制，并全面概述了三萜类化合物在 CVD 管理中的治疗潜力。© 2024。韩国药学会。

Cardiovascular diseases (CVDs) involve dysfunction of the heart and blood vessels and have become major health concerns worldwide. Multiple mechanisms may be involved in the occurrence and development of CVDs. Although therapies for CVDs are constantly being developed and applied, the incidence and mortality of CVDs remain high. The roles of natural compounds in CVD treatment are being explored, providing new approaches for the treatment of CVD. Pentacyclic triterpenes are natural compounds with a basic nucleus of 30 carbon atoms, and they have been widely studied for their potential applications in the treatment of CVDs, to which various pharmacological activities contribute, including anti-inflammatory, antioxidant, and antitumor effects. This review introduces the roles of triterpenoids in the prevention and treatment of CVDs, summarizes their potential underlying mechanisms, and provides a comprehensive overview of the therapeutic potential of triterpenoids in the management of CVDs.© 2024. The Pharmaceutical Society of Korea.