研究动态
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用于预防癌症的生物共轭物:产生影响的机会。

Bioconjugates for Cancer Prevention: Opportunities for Impact.

发表日期:2024 Aug 08
作者: Erin Lavik, Lori Minasian
来源: BIOCONJUGATE CHEMISTRY

摘要:

癌症预防包括在癌症最有可能治愈时及早发现癌症的筛查策略以及降低患癌症风险的预防和拦截策略。生物共轭物在这里广泛定义为具有合成和生物成分的材料和分子,在整个癌症预防领域发挥着作用。特别是,生物结合物可以被开发为负担得起的、可获得的和有效的筛查策略,或者作为新型疫苗和药物来降低患癌症的风险。开发计划可用于采用新技术并评估它们在癌症筛查和预防中的临床应用。虽然实施癌症预防干预措施存在各种不同的挑战,但深思熟虑的生物结合物方法可以改善干预措施的实施和可接受性。
Cancer prevention encompasses both screening strategies to find cancers early when they are likely to be most treatable and prevention and interception strategies to reduce the risk of developing cancers. Bioconjugates, here defined broadly as materials and molecules that have synthetic and biological components, have roles to play across the cancer-prevention spectrum. In particular, bioconjugates may be developed as affordable, accessible, and effective screening strategies or as novel vaccines and drugs to reduce one's risk of developing cancers. Developmental programs are available for taking novel technologies and evaluating them for clinical use in cancer screening and prevention. While a variety of different challenges exist in implementing cancer-prevention interventions, a thoughtful approach to bioconjugates could improve the delivery and acceptability of the interventions.