巴西南部猫中与猫白血病病毒 (FeLV) 相关的肿瘤和非肿瘤疾病。
Neoplastic and non-neoplastic diseases associated with feline leukaemia virus (FeLV) in cats in southern Brazil.
发表日期:2024 Aug 13
作者:
Gustavo Willian Pandolfo, Thierry Grima de Cristo, Jéssica Aline Withoeft, Jennyfer Júlia da Silva Sá, Maria Augusta Fornara, Aline Viebrantz, Mariana Casa, Claudia Salete Wisser, Renata Assis Casagrande
来源:
Comp Immunol Microb
摘要:
本研究的目的是对与猫 FeLV 感染相关的疾病进行分类。总共 154 只猫接受了尸检、组织病理学检查和抗 FeLV 免疫组织化学 (IHC),其中 83 只 (50.9%) IHC FeLV 呈阳性。猫的平均年龄为4.1岁,其中幼猫占3.6%,幼猫占34.9%,壮猫占37.4%,成年猫占18.1%,老年猫占2.4%,年龄未知占3.6%。肿瘤性疾病最为常见,其中以白血病和淋巴瘤为主,其次是病毒性疾病、细菌性疾病、创伤性疾病、退行性疾病、中毒性疾病、寄生虫性疾病、畸形性疾病等。 FeLV 猫被诊断出患有肿瘤的可能性是其他疾病的 5.73 倍。 FeLV 猫患白血病(OR = 7.75)和淋巴瘤(OR = 6.75)的比值比(OR)高于其他肿瘤。 FeLV 感染在混合品种中更为普遍,从幼年到成年的雄性,患有肿瘤疾病,包括白血病和淋巴瘤。因此,由于 FeLV 的高发病率,了解与 FeLV 相关的疾病在巴西至关重要,这可能会鼓励实施预防措施以减少其传播。版权所有 © 2024 Elsevier Ltd。保留所有权利。
The objective of this study was to categorise diseases associated with FeLV infection in cats. A total of 154 cats were submitted to necropsy, histopathology exam and anti-FeLV immunohistochemistry (IHC), and 83 (50.9 %) were IHC FeLV-positive. The cats age means of 4.1 years, including 3.6 % kittens, 34.9 % junior, 37.4 % prime, 18.1 % mature, 2.4 % senior, 3.6 % unknown age. Neoplastic diseases were most prevalent with leukaemia and lymphoma being most predominant, followed by viral diseases, bacterial, trauma, degenerative, intoxications, parasitic, malformation and others. FeLV+ cats were 5.73 times more likely to be diagnosed with neoplasms than other diseases. The odds ratio (OR) of FeLV+ cats developing leukaemia (OR = 7.75) and lymphoma (OR = 6.75) was higher than other neoplasms. FeLV infection was more prevalent in the mixed breed, junior to prime, male, with neoplastic diseases, including leukaemia and lymphoma. Therefore, understanding the diseases associated with FeLV is of paramount importance in Brazil due to its high prevalence, and it may encourage the implementation of prophylactic measures to reduce its dissemination.Copyright © 2024 Elsevier Ltd. All rights reserved.