化疗引起的周围神经病变（CIPN）可能导致治疗延迟或停止。运动可以改善 CIPN，但效果并不一致。从数据库建库到 2023 年 12 月 22 日，检索了 12 个数据库和 5 个网站，查找以英文报道的初步研究，探讨了运动对癌症幸存者 CIPN 的影响。 20 项研究确定并审查了（N = 1,308 名参与者）。使用随机效应模型，锻炼稍微改善了 CIPN 的症状（Hedges g = 0.28，Hartung-Knapp 调整 95% 置信区间 [0.12, 0.45]，p = 0.002）。 95% 的预测区间表明，未来研究的真实效应大小可能在 -0.1 到 0.66 之间。进行锻炼的频率可以调节效果大小，进一步改善症状。护士可以鼓励癌症幸存者进行锻炼，例如阻力训练、有氧运动、平衡训练和/或瑜伽。护士可以将癌症幸存者转介给经过培训的运动专家，或提供有关为癌症患者寻找社区运动计划的信息。

Chemotherapy-induced peripheral neuropathy (CIPN) can cause treatment delays or discontinuation. Exercise can improve CIPN, but the effects have been inconsistent.12 databases and 5 websites were searched from database inception to December 22, 2023, for primary studies that were reported in English and examined the effects of exercise on CIPN in cancer survivors.20 studies (N = 1,308 total participants) were identified and reviewed.Using a random-effects model, exercise slightly improved symptoms of CIPN (Hedges's g = 0.28, Hartung-Knapp adjusted 95% confidence interval [0.12, 0.45], p = 0.002). The 95% prediction interval showed that the true effect size of future studies would likely range from -0.1 to 0.66. Frequency of performing exercise moderated the effect size, further improving symptoms.Nurses can encourage cancer survivors to engage in exercise, such as resistance training, aerobic exercise, balance training, and/or yoga. Nurses can refer cancer survivors to trained exercise specialists or provide information about finding a community exercise program for patients with cancer.