研究动态
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骨和软组织肉瘤患者的心理健康障碍和手术结果。

Mental Health Disorders and Surgical Outcomes in Patients With Bone and Soft Tissue Sarcoma.

发表日期:2024 Aug 19
作者: MaKenzie M Chambers, Caroline T Gutowski, Pietro Gentile, Krystal Hunter, Tae Won B Kim, Christina J Gutowski
来源: Bone & Joint Journal

摘要:

我们进行了一项研究,旨在调查患有骨和软组织肉瘤的骨科患者的心理健康诊断 (MHD) 与术后结果之间的关系。我们假设术前患有 MHD 的肉瘤患者的预后会更差,术后并发症也会更多。对 356 名接受骨或软组织肉瘤手术治疗的患者进行了回顾性研究。患者被分为两组:一组被诊断为抑郁症、焦虑症、双相情感障碍和/或精神分裂症,另一组之前没有 MHD。使用独立 t、Mann-Whitney U 和卡方检验进行统计分析。统计分析表明 MHD 组和对照组在三个结果上存在显着差异:住院时间、90 天再入院率和手术发生率部位感染。 MHD 组的亚组分析显示,肉瘤治疗期间确诊的患者 90 天再入院率显着较高。肉瘤和 MHD 患者术后住院时间较长,90 天再入院率较高,手术风险较高部位感染。鉴于全国范围内精神健康障碍的患病率不断上升,骨科医生应该意识到患有和不患有精神疾病的肉瘤患者术后结果的差异。 [骨科。 20XX;4X(X):XXX-XXX.]。
We conducted a study to investigate the relationship between a mental health diagnosis (MHD) and postoperative outcomes in orthopedic patients with bone and soft tissue sarcoma. We hypothesized that patients with sarcoma with a preoperative MHD would have worse outcomes and more postoperative complications.A retrospective review was performed of 356 patients who underwent surgical treatment for bone or soft tissue sarcoma. Patients were divided into two groups: those with a diagnosis of depression, anxiety, bipolar disorder, and/or schizophrenia and those with no previous MHD. Statistical analysis was performed using independent t, Mann-Whitney U, and chi-square tests.Statistical analysis demonstrated significant differences between the MHD group and the control group in three outcomes: length of stay, 90-day readmission rate, and incidence of surgical site infections. Subgroup analysis of the MHD group yielded significantly higher 90-day readmission rates for patients who were diagnosed during sarcoma treatment.Patients with sarcoma and an MHD had a longer postoperative hospital stay, an increased 90-day readmission rate, and a greater risk of surgical site infection. Given the rising prevalence of mental health disorders nationwide, orthopedic surgeons should be aware of differences in postoperative outcomes between patients with sarcoma with and without mental illness. [Orthopedics. 20XX;4X(X):XXX-XXX.].