为了确定种族/族裔是否在妇科恶性肿瘤患者的临床试验知识中发挥作用。在一家三级医疗中心进行了一项横断面调查。参与者是患有妇科恶性肿瘤的成年人（≥18 岁），并且懂英语、西班牙语或中文。参与者完成了 9 项临床试验知识评估。使用描述性统计总结人口统计特征。采用多变量模型来评估种族/民族与临床试验知识之间的关系。接触了 245 名患者，其中 25 名（10.2%）拒绝了。在参与者中，108 名（50.2%）是白人，107 名（49.8%）是有色人种。年龄、教育程度、出生地和收入方面存在显着差异；没有观察到癌症类型或阶段的差异。知识评估的正确答案中位数为七个。 67 名 (62%) 白人与 26 名 (24.3%) 有色人种的临床试验知识得分高于平均水平 (p < 0.001)。多变量分析显示，白人参与者临床试验知识得分高于平均水平的可能性是白人参与者的 2.7 倍。白人参与者总体上利用了更多的资源。与非老年人（<65 岁）相比，老年人（≥65 岁）对临床试验的了解更高；然而，这些发现并不显着。这项研究观察到被诊断患有妇科恶性肿瘤的白人和有色人种在临床试验知识方面存在显着差异。与有色人种相比，白人患者利用更多的信息资源。进一步的研究需要开发资源和推广机制，以增加临床试验参与的机会和多样性。版权所有 © 2024 Elsevier Inc. 保留所有权利。

To identify whether race/ethnicity plays a role in knowledge of clinical trials among patients with a gynecologic malignancy.A cross-sectional survey was conducted at a tertiary medical center. Participants were adults (≥18 years old), with gynecologic malignancy, and literate in English, Spanish or Chinese. Participants completed a 9-item clinical trial knowledge assessment. Demographic characteristics were summarized using descriptive statistics. A multivariable model was employed to evaluate the relationship between race/ethnicity and clinical trial knowledge.245 patients were approached, 25 (10.2%) declined. Among participants, 108 (50.2%) were white, and 107 (49.8%) were people of color. Significant differences were noted for age, education, birthplace, and income; no difference was observed for cancer type or stage. The median number of correct answers for the knowledge assessment was seven. 67 (62%) white vs 26 (24.3%) people of color had an above average clinical trial knowledge score (p < 0.001). Multivariable analysis showed white participants were 2.7 times more likely to have an above average clinical trial knowledge score. White participants overall utilized more resources. Elder adults (≥65 years old) had higher knowledge of clinical trials compared to non-elder adults (<65 years old); however, these findings were not significant.This study observed significant differences in clinical trial knowledge between white and people of color diagnosed with a gynecologic malignancy. White patients utilize more informational resources compared to people of color. Further studies need to develop resources and outreach mechanisms that will increase access and diversity in clinical trial participation.Copyright © 2024 Elsevier Inc. All rights reserved.