代谢综合征（MetS）是心血管疾病（CVD）的危险因素，而CVD是癌症患者面临的主要挑战。本研究旨在调查成年癌症患者中 MetS 与 CVD 的患病率及其关联。这项横断面研究纳入了 2007 年至 2018 年国家健康与营养检查调查 (NHANES) 中年龄≥18 岁的癌症患者。 CVD采用加权分析法计算。使用多变量逻辑回归来评估 MetS 和 CVD 之间的关联。该研究纳入了 2658 名成年癌症患者，其中 1260 名表现出 MetS，636 名患有 CVD。癌症患者MetS和CVD的加权患病率分别为45.44%和19.23%。多变量逻辑回归显示，患有 MetS 的癌症患者 CVD 患病率较高的风险增加了 79%，OR (95% CI) 为 1.79 (1.31, 2.44)。值得注意的是，在调整协变量后，MetS 成分中的肥胖、血压升高 (BP)、高血糖和低高密度脂蛋白胆固醇 (HDL-C) 与较高的 CVD 患病率显着相关。此外，癌症患者的 CVD 患病风险随着 MetS 成分的增加而增加。值得注意的是，在 65 岁以下的患者和女性中，MetS 与 CVD 的相关性更强。在成年癌症患者中，超过五分之二 (45.44%) 被认为患有 MetS，而大约五分之一 (19.23%) 被认为患有 CVD 。值得注意的是，肥胖、血压升高、高血糖、低 HDL-C 和较高的 MetS 成分被发现与成人癌症患者较高的 CVD 患病率显着相关。 65 岁以下的癌症患者和患有 MetS 的女性患 CVD 的风险可能增加。© 2024。作者。

Metabolic syndrome (MetS) is a risk factor for cardiovascular disease (CVD), and CVD is a major challenge for cancer patients. This study aimed to investigate the prevalence and association of MetS and CVD among adult cancer patients.This cross-sectional study included cancer patients aged > 18 years from the National Health and Nutrition Examination Survey (NHANES) from 2007 to 2018. The prevalence of MetS and CVD was calculated using weighted analysis. Multivariable logistic regression was used to assess the association between MetS and CVD.The study included 2658 adult cancer patients, of whom 1260 exhibited MetS and 636 had CVD. The weighted prevalence of MetS and CVD in cancer patients was 45.44%, and 19.23%, respectively. Multivariable logistic regression showed a 79% increased risk in higher CVD prevalence in cancer patients with MetS, with the OR (95% CI) of 1.79 (1.31, 2.44). Notably, obesity, elevated blood pressure (BP), high glucose, and low high density lipoprotein cholesterol (HDL-C) in the MetS components were significantly associated with higher CVD prevalence after adjusting for covariates. Moreover, the risk of CVD prevalence in cancer patients increased with more MetS components. Notably, MetS was more strongly linked to CVD in patients aged < 65 and women.Among adult cancer patients, over two-fifths (45.44%) were estimated to have MetS, while about one-fifth (19.23%) were considered to have CVD. Notably, obesity, elevated BP, high glucose, low HDL-C, and higher number of MetS components were found to be significantly associated with higher CVD prevalence among cancer adults. Cancer patients under 65 and women with MetS may be at increased risk of CVD.© 2024. The Author(s).