这项荟萃分析检查了术前振动控制瞬时弹性成像 (VCTE) 是否可以预测接受肝细胞癌 (HCC) 肝切除术的患者的术后并发症和复发。使用 Ovid-Medline、EMBASE、Cochrane 和韩国医学进行了系统文献检索数据库。在 431 项单独研究中，包括 2008 年至 2022 年期间发表的 13 项研究。 5 项研究关注 HCC 复发，8 项研究术后并发症。五项 HCC 复发研究的荟萃分析显示，VCTE 评分高的高危人群肝切除后复发率显着增加（风险比 [HR] ，2.14）。 HCC复发高危组的VCTE截断值为7.4~13.4kPa，敏感性为0.60（95% CI 0.47~0.72），特异性为0.60（95% CI 0.46~0.72）。通过 VCTE 测量的肝脏硬度预测 HCC 复发的受试者工作特征曲线 (AUC) 下面积为 0.63 (95% CI 0.59-0.67)。术后并发症的荟萃分析显示，VCTE值较高的高危组（12-25.6kPa）术后并发症的风险显着增加（风险比[RR]，8.32）。 VCTE测量肝脏硬度预测术后并发症的AUC为0.87（95% CI 0.84-0.90），敏感性为0.76（95% CI 0.55-0.89），特异性为0.85（95% CI 0.73-0.92）这项荟萃分析表明，对因 HCC 进行肝切除术的患者进行术前 VCTE 有助于识别术后并发症和 HCC 复发风险较高的个体。

This meta-analysis examined whether preoperative vibration-controlled transient elastography (VCTE) can predict postoperative complications and recurrence in patients undergoing hepatic resection for hepatocellular carcinoma (HCC).A systematic literature search was conducted using Ovid-Medline, EMBASE, Cochrane, and KoreaMed databases. Out of 431 individual studies, thirteen published between 2008 and 2022 were included. Five studies focused on HCC recurrence, while eight examined postoperative complications.The meta-analysis of five studies on HCC recurrence showed that the high-risk group with a high VCTE score had a significantly increased recurrence rate after hepatic resection (hazard ratio [HR], 2.14). The cutoff value of VCTE in the high-risk group of HCC recurrence was 7.4-13.4kPa, the sensitivity was 0.60 (95% CI 0.47-0.72), and the specificity was 0.60 (95% CI 0.46-0.72). The area under the receiver operating characteristic curve (AUC) of the liver stiffness measured by VCTE to predict the HCC recurrence was 0.63 (95% CI 0.59-0.67). The meta-analysis on the postoperative complications revealed a significantly increased risk of postoperative complications in the high-risk group (12-25.6kPa) with a high VCTE value (risk ratio [RR], 8.32). The AUC of the liver stiffness measured by VCTE to predict the postoperative complications was 0.87(95% CI 0.84-0.90), the sensitivity was 0.76 (95% CI 0.55-0.89) and the specificity was 0.85 (95% CI 0.73-0.92).This meta-analysis suggests that preoperative VCTE in patients undergoing hepatic resection for HCC is useful in identifying individuals at a high risk of postoperative complications and HCC recurrence.