EB 病毒 (EBV) 是一种在全世界成年人中高度流行的病毒。在免疫功能正常的个体中，EBV 感染通常会导致病毒终生潜伏，并且不会产生后遗症。然而，在免疫功能障碍的情况下，EBV 可诱发自身免疫性疾病、增生性增殖和癌症（包括淋巴瘤）的发展。在这里，我们探讨了 EBV 在伯基特淋巴瘤、弥漫性大 B 细胞淋巴瘤、霍奇金淋巴瘤、浆母细胞淋巴瘤、淋巴瘤样肉芽肿、移植后淋巴增殖性疾病以及与免疫缺陷和失调相关的淋巴增殖性疾病中的致病和致癌作用。除了描述 EBV 相关肿瘤发生的一般机制外，我们还讨论了每种疾病背景下 EBV 相关肿瘤发生及其微观、表型和临床表现。

Epstein-Barr virus (EBV) is a highly prevalent virus among adults worldwide. In an immunocompetent individual, EBV infection generally results in lifelong latency of the virus and no sequelae. However, in the setting of immune dysfunction, EBV can induce the development of autoimmune disorders, hyperplastic proliferations, and cancers, including lymphoma. Here, we explore the pathogenic and oncogenic role of EBV in Burkitt lymphoma, diffuse large B-cell lymphoma, Hodgkin lymphoma, plasmablastic lymphoma, lymphomatoid granulomatosis, and post-transplant lymphoproliferative disorders and lymphoproliferative disorders associated with immune deficiency and dysregulation. In addition to describing general mechanisms of EBV-associated oncogenesis, we also discuss EBV-associated oncogenesis in the context of each disorder, as well as their microscopic, phenotypic, and clinical presentations.