研究动态
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年轻患者的乳腺癌存活率:挑战和机遇 - 叙述回顾。

Breast cancer survivorship among younger patients: challenges and opportunities-narrative review.

发表日期:2024 Aug 13
作者: Sandy Vuong, Ellen Warner
来源: PHYSICAL THERAPY & REHABILITATION JOURNAL

摘要:

患有乳腺癌 (YWBC) 的年轻女性面临着独特的生存挑战,因为她们在生命中更脆弱的阶段被诊断出来,并在育龄期间接受性腺毒性和/或抗雌激素治疗。本文的目的是详细阐述这些挑战,并展示专门为 YWBC 量身定制的专门支持性护理计划如何能够极大地促进提供干预措施来应对这些挑战。使用的数据库是 PubMed 和 Medline。文章包括涉及患有乳腺癌的年轻女性和生存护理需求的文章。与老年乳腺癌患者相比,YWBC 通常需要更积极的治疗,并且其疾病更有可能具有遗传基础。常见的挑战包括生育问题、过早绝经、身体形象问题、对癌症复发的过度恐惧、亲密关系的困难以及经济毒性。解决这些需求的一个可能的解决方案是专门支持性护理计划中的纵向护理,例如加拿大安大略省多伦多的年轻乳腺癌女性 PYNK 计划。此类干预措施的例子包括快速保留生育能力、积极管理医源性更年期症状、同伴支持小组以及为患者及其家人提供个性化的社会心理支持。通过满足这一人群的独特需求,支持性护理计划可以在帮助患有乳腺癌的年轻女性应对治疗期间和治疗后可能面临的身体、情感和实际挑战方面发挥至关重要的作用。限制在于资源的可用性和可持续发展的资金。需要持续进行研究,以更好地了解 YWBC 患者的生存需求,并确保旨在应对这些挑战的计划的可持续性。
Young women with breast cancer (YWBC) face unique survivorship challenges due to being diagnosed at a more vulnerable stage in life and receiving gonadotoxic and/or antiestrogen therapy during their reproductive years. The purpose of this article is to elaborate on these challenges and demonstrate how specialized supportive care programs tailored specifically for YWBC, can greatly facilitate the provision of interventions to address these challenges.The databases used were PubMed and Medline. Articles included those that involve young women with breast cancer and survivorship care needs.Compared to older breast cancer patients, YWBC generally require more aggressive treatments and are more likely to have a hereditary basis for their disease. Common challenges include childbearing concerns, premature menopause, body image issues, excessive fear of cancer recurrence, difficulties with intimate relationships, and financial toxicity. A possible solution to addressing these needs are longitudinal care in a specialized supportive care program, such as the PYNK Program for Young Women with Breast Cancer in Toronto, Ontario, Canada. Examples of such interventions include fast-tracking fertility preservation, aggressive management of symptoms of iatrogenic menopause, peer support groups, as well as individualized psycho-social support for the patient and her family.By addressing the unique needs of this population, supportive care programs can play a crucial role in empowering young women with breast cancer to cope with the physical, emotional, and practical challenges they may face during and after treatment. The limitation lies in resource availability and funding for sustainability. Ongoing research is required to better understand the needs of YWBC patients in survivorship and ensure the sustainability of programs designed to address these challenges.