关于预防放射性皮炎的产品的证据有限。主要目的是分析喷雾皮肤保护剂“不燃烧屏障膜”与基于金盏花的标准化保湿剂相比，在护理咨询中预防肛管癌和直肠癌患者出现湿性脱屑放射性皮炎的有效性和库拉索芦荟。单盲随机临床试验。该研究在巴西里约热内卢的一家医院进行，63 名接受肛管癌和直肠癌治疗的患者被随机分为以下两组之一：实验组使用喷雾皮肤保护剂，对照组则使用喷雾皮肤保护剂。使用保湿霜。使用初始和后续评估表收集数据，并使用描述性和推理性分析进行评估。与对照组相比，使用喷雾皮肤保护剂的参与者出现伴有湿性脱屑的放射性皮炎的可能性较低，并且没有这种结果的时间较长。放射性皮炎总发病率为100%，其中重症率为36.5%。此外，17.5% 的参与者因放射性皮炎而停止放疗。放射性皮炎的严重程度和停止放疗的患者数量在各组之间没有差异。该皮肤保护剂可有效预防肛管癌和直肠癌患者的放射性皮炎伴湿性脱屑。© 2024 作者。 《国际伤口杂志》由 Medicalhelplines.com Inc 和 John Wiley 出版

The evidence on products for the prevention of radiodermatitis is limited. The primary objective was to analyse the effectiveness of the spray skin protectant 'non-burning barrier film' in the prevention of radiodermatitis with moist desquamation in patients with the anal canal and rectal cancer followed in nursing consultations compared to a standardised moisturiser based on Calendula officinalis and Aloe barbadensis. Single-blind randomised clinical trial. The study was performed in a hospital in Rio de Janeiro, Brazil, with 63 patients undergoing anal canal and rectal cancer treatment, randomised into one of the following two groups: an experimental group, which used a spray skin protectant and a control group, which used a moisturiser. Data were collected using an initial and subsequent evaluation form and were assessed using descriptive and inferential analyses. Participants who used the spray skin protectant had a lower chance of presenting radiodermatitis with moist desquamation and a longer time without this outcome when compared to the control group. The overall incidence of radiodermatitis was 100%, with 36.5% being severe. Furthermore, 17.5% of participants discontinued radiotherapy due to radiodermatitis. There were no differences between the groups regarding the severity of radiodermatitis and the number of patients who discontinued radiotherapy. The skin protectant was effective in preventing radiodermatitis with moist desquamation amongst patients with anal canal and rectal cancer.© 2024 The Author(s). International Wound Journal published by Medicalhelplines.com Inc and John Wiley & Sons Ltd.