癌症是世界上最重要的社会挑战之一，每年有超过 2300 万新发病例和 1000 万人死亡，只有更加注重预防才能妥善解决这一问题。这需要民众知情、了解风险因素并愿意采取预防行为和早期癌症筛查。为此，制作了《2分钟改变生活的分钟》，这是有史以来第一个关于癌症预防的电视娱乐教育系列节目。本研究旨在评估“2 分钟改变生活”（一种用于预防癌症的新型 E-E 形式）对知识获取和行为改变的影响。进行了两项补充研究，总共涉及 1314 名参与者：一项针对该系列剧的潜在观众的测试筛选 (TS) 研究，以及一项针对那些自发在电视上观看该系列剧的人的自然筛选 (NS) 研究。我们发现（i）非常高水平的欣赏和叙事参与度，并且愿意观看更多剧集； (ii) 在所有四个测试主题上，统计上显着的知识增益，范围为 17% 到 44%； (iii) 有效行为改变的证据。回归分析表明，叙事参与度是行为改变的最佳预测因子[NS：比值比（OR） = 3.38，95%置信区间（CI） = 1.70-6.74，p = 0.001； TS：OR = 2.05，95% CI = 1.13-0.371，p = 0.018]。这项研究展示了该系列节目的真正影响，并作为癌症预防新策略的概念验证，该策略基于令人信服的健康叙述，而不是信息或数据，以吸引观众、增加知识并诱导行为改变。©作者 2024。由牛津大学出版社出版。版权所有。如需商业重复使用，请联系 reprints@oup.com 获取转载和转载的翻译权。所有其他权限均可通过我们网站文章页面上的“权限”链接通过我们的 RightsLink 服务获得 - 欲了解更多信息，请联系journals.permissions@oup.com。

Cancer is one of the most important societal challenges in the world, with over 23 million new cases/year and 10 million deaths/year, that will only be properly tackled with a stronger focus on prevention. This calls for an informed population, aware of risk factors and willing to adopt preventive behaviors and early cancer screenings. For that purpose, 2' Life-changing minutes was created, the first ever televised Entertainment-Education series on cancer prevention. This study aims to evaluate the impact of 2' Life-changing minutes, a novel E-E format for cancer prevention, on knowledge gains and behavior changes. Two complementary studies were performed involving a total of 1314 participants: a test-screening (TS) study targeting potential viewers of the series, and a natural-screening (NS) study targeting those that spontaneously watched the series on television. We found (i) very high levels of appreciation and narrative engagement, and also willingness to see more episodes; (ii) statistically significant knowledge gains, ranging from 17% to 44%, on all four topics tested; (iii) evidence of effective behavior change. Regression analysis showed that narrative engagement was the best predictor of behavior change [NS: odds ratio (OR) = 3.38, 95% confidence interval (CI) = 1.70-6.74, p = 0.001; TS: OR = 2.05, 95% CI = 1.13-0.371, p = 0.018]. This study demonstrates the series' real impact and serves as a proof-of-concept for a novel strategy of cancer prevention that is based around compelling health narratives, rather than information or data, to engage viewers, increase knowledge and induce behavior change.© The Author(s) 2024. Published by Oxford University Press. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.