基因组研究的最新进展越来越多地关注脂肪量和肥胖相关（FTO）基因，因为它与肥胖具有显着的相关性。 FTO 最初是因其对增加体重的贡献而被探索，后来发现它具有 m6A 去甲基酶的功能。这一关键作用增强了我们对其对各种病理学更广泛影响的理解。 m6A 等表观遗传修饰与妇科癌症有关，包括卵巢癌、子宫内膜癌和宫颈癌。然而，FTO 影响妇科癌症发展的确切机制仍然很大程度上未知。该分析强调了 FTO 基因研究在阐明妇科癌症潜在机制和探索潜在治疗途径方面日益重要的相关性。版权所有 © 2024 Wang 和 Liu。

Recent advances in genomic research have increasingly focused on the fat mass- and obesity-associated (FTO) gene due to its notable correlation with obesity. Initially explored for its contribution to increased body weight, FTO was later discovered to function as an m6A demethylase. This pivotal role enhances our understanding of its broader implications across various pathologies. Epigenetic modifications, such as m6A, have been implicated in gynecological cancers, including ovarian, endometrial, and cervical malignancies. However, the precise mechanisms by which FTO influences the development of gynecological cancers remain largely unknown. This analysis underscores the growing relevance of investigations into the FTO gene in elucidating the mechanisms underlying gynecological cancers and exploring potential therapeutic avenues.Copyright © 2024 Wang and Liu.