简介：纳米银（AgNPs）由于其独特的理化性质而在生物医学应用中受到广泛关注。本综述重点关注 AgNP 在抗菌活性、抗癌治疗和伤口愈合中的作用，强调其解决关键健康挑战的潜力。方法：使用 Scopus 数据库中的出版物进行文献计量分析，涵盖 2002 年至 2024 年的研究。该研究包括关键词频率、引用模式和作者网络。数据由 Zotero 管理，并使用 Bibliometrix R 和 VOSviewer 进行分析以实现网络可视化。结果：该研究揭示了 AgNP 研究的增长趋势，特别是在抗菌应用方面，共发表了 8,668 篇论文。随后的抗癌和伤口愈合应用，其中印度和中国做出了重大贡献。分析显示，人们越来越关注“绿色合成”方法，凸显了向可持续生产的转变。主要研究结果表明，AgNP 在对抗多重耐药细菌、诱导癌细胞凋亡以及促进伤口愈合中的组织再生方面具有有效性。讨论：AgNP 的广泛研究和应用强调了它们在医疗干预中的多功能性。该研究强调了可持续合成方法的必要性，并强调了潜在风险，例如长期毒性和环境影响。未来的研究应侧重于优化临床使用的 AgNP 制剂并进一步了解其作用机制。结论：AgNPs 在现代医学中发挥着关键作用，特别是在解决抗菌素耐药性、癌症治疗和伤口处理方面。持续的研究和国际合作对于促进 AgNP 在医疗保健中的安全有效使用至关重要。版权所有 © 2024 Jangid、Singh、Kashyap、Singh 和 Kumar。

Introduction: Silver nanoparticles (AgNPs) have gained significant attention in biomedical applications due to their unique physicochemical properties. This review focuses on the roles of AgNPs in antimicrobial activity, anticancer therapy, and wound healing, highlighting their potential to address critical health challenges. Methods: A bibliometric analysis was conducted using publications from the Scopus database, covering research from 2002 to 2024. The study included keyword frequency, citation patterns, and authorship networks. Data was curated with Zotero and analyzed using Bibliometrix R and VOSviewer for network visualizations. Results: The study revealed an increasing trend in research on AgNPs, particularly in antimicrobial applications, leading to 8,668 publications. Anticancer and wound healing applications followed, with significant contributions from India and China. The analysis showed a growing focus on "green synthesis" methods, highlighting a shift towards sustainable production. Key findings indicated the effectiveness of AgNPs in combating multidrug-resistant bacteria, inducing apoptosis in cancer cells, and promoting tissue regeneration in wound healing. Discussion: The widespread research and applications of AgNPs underscore their versatility in medical interventions. The study emphasizes the need for sustainable synthesis methods and highlights the potential risks, such as long-term toxicity and environmental impacts. Future research should focus on optimizing AgNP formulations for clinical use and further understanding their mechanisms of action. Conclusion: AgNPs play a pivotal role in modern medicine, particularly in addressing antimicrobial resistance, cancer treatment, and wound management. Ongoing research and international collaboration are crucial for advancing the safe and effective use of AgNPs in healthcare.Copyright © 2024 Jangid, Singh, Kashyap, Singh and Kumar.