神经周围扩散（PNS）与头颈皮肤鳞状细胞癌（cSCCHN）的不良预后相关。因此，调查 cSCCHN 中 PNS 早期诊断和治疗的促进因素和障碍可能会改善结果。患者是从机构数据库中招募的。根据治疗途径模型进行半结构化访谈。主题分析基于框架中的四个主要区间，采用数据驱动的分析方法。对 17 名参与者进行了访谈。促进因素包括患者过去的经历、症状进展、对医疗保健专业人员 (HCP) 的信任以及利用关系的能力。障碍包括诊断困难、获得癌症服务的机会有限、缺乏护理协调以及初级卫生保健提供者缺乏对 PNS 的认识。这些发现强调了 PNS 早期诊断和治疗的复杂性。临床实践指南、医护人员教育和远程医疗等干预措施可以促进及时检测和管理。© 2024 作者。约翰·威利出版的癌症医学

Perineural spread (PNS) is associated with a poor prognosis in cutaneous squamous cell carcinoma of the head and neck (cSCCHN). Hence, investigating facilitators and barriers of early diagnosis and treatment of PNS in cSCCHN may improve outcomes.Patients were recruited from an institutional database. Semi-structured interviews were conducted according to the Model of Pathways to Treatment. Thematic analysis was based on the four main intervals in the framework using a data-driven analytical method.Seventeen participants were interviewed. Facilitators included patients' past experiences, symptom progression, trust in healthcare professionals (HCPs), and capacity to leverage relationships. Barriers included difficult diagnoses, limited access to cancer services, lack of care coordination, and lack of awareness of PNS among primary health care providers.These findings emphasise the complexity early diagnosis and treatment of PNS. Interventions like clinical practice guidelines, education for HCPs, and telehealth could facilitate timely detection and management.© 2024 The Author(s). Cancer Medicine published by John Wiley & Sons Ltd.