研究动态
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焦亡在前列腺癌发生和进展中的作用:研究进展。

[Pyroptosis in the development and progression of prostate cancer: Progress in research].

发表日期:2024 Feb
作者: Qi Zhao, Kang-Wei Zuo, Wei-Ping Li
来源: Cell Death & Disease

摘要:

细胞焦亡作为一种新的程序性死亡模式,在前列腺癌的发生、发展过程中发挥着重要作用,针对细胞焦亡途径的药物作为一种新的治疗策略,可能会对前列腺癌的治疗产生重大影响。然而,细胞焦亡的确切机制仍不清楚,需要进一步研究。本文总结了近年来细胞焦亡在前列腺癌中的作用。它包括对焦亡机制、其在前列腺癌发展中的作用及其临床应用的讨论。这将为临床医生提供新的治疗和药物开发策略。
Pyroptosis, as a new programmed death mode, plays an important role in the development and progression of prostate cancer, and the drugs targeting the pyroptosis pathway, as a new therapeutic strategy, may produce a significant influence on the treatment of prostate cancer . However, the precise mechanism of cellular pyroptosis remains unclear, necessitating further investigation. This paper presents a summary of the role of cellular pyroptosis in prostate cancer over recent years. It includes a discussion of the mechanism of pyroptosis, its role in prostate cancer development, and its clinical applications. This will provide clinicians with a new strategy for treatment and drug development.