口腔粘膜恶性黑色素瘤（OMMM）起源于恶性黑色素细胞，发病年龄、性别和部位分别为20～83岁、男性、硬腭粘膜和上颌牙龈粘膜。尽管文献中已发表多例 OMMM 病例，但种植牙周围发生恶性黑色素瘤的病例却很少报道。 一名 59 岁男性因种植牙治疗 3 年后出现牙龈黑色素沉着入院。年。口内检查发现上颌牙龈和种植牙（第一磨牙）牙槽窝周围有无痛性黑色分叶状肿块。 CBCT 显示种植体周围的骨质破坏。正电子发射断层扫描/计算机断层扫描证实存在肿瘤病变，诊断为右上颌牙龈恶性黑色素瘤（T4aN0M0）。进行上颌部分切除颊脂垫转移游离组织补片修复。病理分析证实了恶性黑色素瘤的诊断。术后过程很顺利，患者正在进行随访，没有任何复发的证据。我们的报告显示，不合适的种植牙可能会导致 OMMM。具有足够手术切缘的切除活检可以完全切除 OMMM 并进行最终诊断。建议早期诊断和治疗。版权所有 © 2024，作者：Mutaz B. Habal，医学博士。

Oral mucosal malignant melanoma (OMMM) arises from malignant melanocytes, and the most affected age, sex, and site are 20 to 83 years, male, and the mucosa of hard palate and maxillary gingiva, respectively. Despite several cases of OMMM have been published in the literature, cases of malignant melanoma arising around the dental implant are rarely reported.A 59-year-old male was admitted to our Department with the complain of gingival black pigmentations following dental implant treatment for 3 years. Intraoral examination revealed a painless black lobulated mass around maxillary gingiva and alveolar fossa of dental implant (first molar). CBCT revealed bone destruction around the implant. Positron emission tomography/computed tomography confirmed the presence of tumoral lesion, which was diagnosed as right maxillary gingiva malignant melanoma (T4aN0M0). Partial maxillectomy+buccal fat pad transfer+free tissue patch repair were carried out. Pathologic analyses confirmed the diagnosis of malignant melanoma. The postoperative course was uneventfully, the patient is undergoing follow-up without any evidence of recurrence.Our report showed that an ill-fitting dental implant may cause OMMM. Excisional biopsy with sufficient surgical margins allows complete removal and final diagnosis of OMMM. Early diagnosis and treatment are recommended.Copyright © 2024 by Mutaz B. Habal, MD.