术中面部运动诱发电位在桥小脑角肿瘤手术中的预测价值
The predictive value of intraoperative facial motor evoked potentials in cerebellopontine angle tumor surgery.
发表日期:2024 Aug 06
作者:
Szu-Yen Pan, Robert N Holdefer, Han-Lin Wu, Chi-Ruei Li, Lanjun Guo
来源:
Best Pract Res Cl Ob
摘要:
我们的目的是探讨术中面部运动诱发电位(FMEP)对桥小脑角(CPA)肿瘤手术中面部结局的价值,为未来的临床实践和前瞻性研究提供循证共识标准。 2023 年 6 月。使用 QUADAS-2 工具评估研究质量。用于荟萃分析和荟萃回归的双变量和随机效应模型生成了汇总受试者工作特征曲线 (ROC) 和森林图,用于估计敏感性和特异性。我们纳入了 17 项研究(1,206 名受试者)。与随访 (FU) 期间 (0.82, 95% CI 0.74-0.88) 相比,术后即刻 (IM) 的敏感性较低 (0.76, 95% CI 0.65-0.84),而两组的特异性相似 (IM) ,0.94,95% CI 0.89-0.97;FU,0.93,95% CI 0.87-0.96)。数据驱动的估计提高了 FMEP 绩效,但需要未来研究的证实。幅度截止标准和将新缺陷评分为比 House-Brackmann (HB) 2 级更差的研究产生了最佳灵敏度。FMEP 证明了面部功能监测具有统计学上显着的准确性。不同研究中 FMEP 的实施差异很大。我们的研究是第一个通过荟萃分析进行的系统评价,旨在证明术中 FMEP 在 CPA 肿瘤手术中对于面部预后具有重要价值。元回归确定了 FMEP 应用中最有用的方法。版权所有 © 2024。由 Elsevier B.V. 出版。
Our aim is to explore the value of intraoperative facial motor evoked potentials (FMEP) for facial outcomes in cerebellopontine angle (CPA) tumor surgery to provide an evidence-based consensus standard for future clinical practice and prospective studies.Electronic databases were searched from inception to June 2023. Study quality was assessed with the QUADAS-2 tool. Bivariate and random-effects models for meta-analysis and meta-regression generated summary receiver operating characteristic curves (ROC) and forest plots for estimates of sensitivity and specificity.We included 17 studies (1,206 participants). Sensitivity was lower in the immediate (IM) post-operative (0.76, 95% CI 0.65-0.84) compared to follow-up (FU) period (0.82, 95% CI 0.74-0.88) while specificity was similar in both groups (IM, 0.94, 95% CI 0.89-0.97; FU, 0.93, 95% CI 0.87-0.96). Data driven estimates improved FMEP performance but require confirmation from future studies. Amplitude cutoff criteria and studies that scored new deficits as worse than House-Brackmann (HB) grade 2 yielded best sensitivities.FMEP demonstrated statistically significant accuracy for facial function monitoring. Implementation of FMEPs varied widely across studies.Our study is the first systematic review with meta-analysis to demonstrate that intraoperative FMEP is valuable in CPA tumor surgery for facial outcomes. Meta-regression identified the methods that were most useful in the application of FMEPs.Copyright © 2024. Published by Elsevier B.V.