内镜检查后上消化道癌症（PEUGIC）是内镜检查质量的重要关键性能指标。我们检查了英格兰内窥镜检查提供者之间的 PEUGIC 率差异，并探讨了相关因素。这是一项基于人群的回顾性病例对照研究，检查了来自国家癌症登记和分析服务以及医院诊断食管癌和胃癌的医院发病统计数据库的数据2009年至2018年在英格兰。 PEUGIC 是在内窥镜检查未诊断出癌症后 6 至 36 个月诊断出的癌症。使用多变量逻辑回归分析确定相关因素。全国内窥镜检查提供者的 PEUGIC 率为 8.5%，范围从 5% 到 13% 不等。与 PEUGIC 相关的因素包括： 女性（比值比 [OR] 1.29 [95%CI 1.23-1.36]）；年龄较小（年龄 >80 岁，OR 0.52 [0.48-0.56]，与 ≤60 岁相比）；合并症增加（Charlson 评分 >4，OR 5.06 [4.45-5.76]）；食管溃疡（OR 3.30 [3.11-3.50]）、巴雷特食管（OR 3.21 [3.02-3.42]）、食管狭窄（OR 1.28 [1.20-1.37]）或胃溃疡（OR 1.55 [1.44-1.66]）病史;鳞状细胞癌（OR 1.50 [1.39-1.61]）；和英国国家内窥镜认证状态 - 提供者需要改进（OR 1.10 [1.01-1.20]），提供者从未评估（OR 1.24 [1.04-1.47]）。内窥镜检查提供者之间的 PEUGIC 率相差三倍，表明内窥镜质量存在不必要的差异。 PEUGIC 与已知与上消化道癌症相关的内窥镜检查结果以及缺乏国家内窥镜检查提供者认证有关。 PEUGIC 变异表明有机会提高性能标准，以更早地发现上消化道癌症并改善结果。作者。这是蒂姆根据知识共享署名-非衍生-非商业许可条款发表的开放获取文章，只要对原始作品给予适当的署名，就允许复制和复制。内容不得用于商业目的，也不得改编、重新混合、转换或构建。 （https://creativecommons.org/licenses/by-nc-nd/4.0/）。

Post-endoscopy upper gastrointestinal cancer (PEUGIC) is an important key performance indicator for endoscopy quality. We examined variation in PEUGIC rates among endoscopy providers in England and explored associated factors.The was a population-based, retrospective, case-control study, examining data from National Cancer Registration and Analysis Service and Hospital Episode Statistics databases for esophageal and gastric cancers diagnosed between 2009 and 2018 in England. PEUGIC were cancers diagnosed 6 to 36 months after an endoscopy that did not diagnose cancer. Associated factors were identified using multivariable logistic regression analyses.The national PEUGIC rate was 8.5%, varying from 5% to 13% among endoscopy providers. Factors associated with PEUGIC included: female sex (odds ratio [OR] 1.29 [95%CI 1.23-1.36]); younger age (age >80 years, OR 0.52 [0.48-0.56], compared with ≤60 years); increasing comorbidity (Charlson score >4, OR 5.06 [4.45-5.76]); history of esophageal ulcer (OR 3.30 [3.11-3.50]), Barrett's esophagus (OR 3.21 [3.02-3.42]), esophageal stricture (OR 1.28 [1.20-1.37]), or gastric ulcer (OR 1.55 [1.44-1.66]); squamous cell carcinoma (OR 1.50 [1.39-1.61]); and UK national endoscopy accreditation status - providers requiring improvement (OR 1.10 [1.01-1.20]), providers never assessed (OR 1.24 [1.04-1.47]).PEUGIC rates varied threefold among endoscopy providers, suggesting unwarranted differences in endoscopy quality. PEUGIC was associated with endoscopy findings known to be associated with upper gastrointestinal cancer and a lack of national endoscopy provider accreditation. PEUGIC variations suggest an opportunity to raise performance standards to detect upper gastrointestinal cancers earlier and improve outcomes.The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).