欧洲胃肠内窥镜学会 (ESGE) 将未选择人群的腺瘤检出率 (ADR) 定为至少 25% 的质量指标。然而，缺乏类似于现实世界实践的汇总观测数据限制了对这一阈值的支持。我们的目的是通过荟萃分析进行系统回顾，以评估基于人群的研究中传统腺瘤检测、息肉检测 (PDR)、盲肠插管、肠道准备和并发症的汇总率。PubMed、Scopus 和 Web of Science截至 2023 年 5 月，我们对数据库进行了检索，以查找报告未选定个体的总体 ADR 的基于人群的研究。采用随机效应模型进行荟萃分析。共纳入 31 项研究，涉及 3 644 561 名受试者。手术质量很高，盲肠插管率高，并发症发生率低。总体汇总 ADR、PDR 和癌症检出率分别为 26.5%（95%CI 23.3% 至 29.7%）、38.3%（95%CI 32.5% 至 44.1%）和 2.7%（95%CI 1.5% 至 3.9） ％）， 分别。 ADR 根据适应症而变化：筛查 33.3%（95%CI 24.5% 至 42.2%），监测 42.9%（95%CI 36.9% 至 49.0%），诊断 24.7%（95%CI 19.5% 至 29.9%），亚组分析显示，粪便潜血试验的筛查率为 34.4%（95%CI 22.0% 至 40.5%），初次结肠镜筛查的筛查率为 26.6%（95%CI 22.6% 至 30.5%）。小型常规腺瘤的合并率为 59.9%（95%CI 43.4% 至 76.3%）。总体锯齿状病变检出率为 12.4%（95%CI 8.8% 至 16.0%）。男性和较高年龄与高于基准的 ADR 显着相关。这项基于现实世界观察研究的第一项荟萃分析支持 ADR 的 ESGE 基准，同时建议根据适应症、性别和年龄使用不同的基准.蒂梅。版权所有。

Adenoma detection rate (ADR) is a quality indicator set at a minimum of 25% in unselected populations by the European Society of Gastrointestinal Endoscopy (ESGE). Nevertheless, a lack of pooled observational data resembling real-world practice limits support for this threshold. We aimed to perform a systematic review with meta-analysis to evaluate the pooled rates for conventional adenoma detection, polyp detection (PDR), cecal intubation, bowel preparation, and complications in population-based studies.The PubMed, Scopus, and Web of Science databases were searched until May 2023 for populational-based studies reporting overall ADR in unselected individuals. A random-effects model was used for meta-analysis.31 studies were included, comprising 3 644 561 subjects. A high quality of procedures was noticeable, with a high cecal intubation rate and low complication rate. The overall pooled ADR, PDR, and rate of cancer detection were 26.5% (95%CI 23.3% to 29.7%), 38.3% (95%CI 32.5% to 44.1%), and 2.7% (95%CI 1.5% to 3.9%), respectively. ADR varied according to indication: screening 33.3% (95%CI 24.5% to 42.2%), surveillance 42.9% (95%CI 36.9% to 49.0%), and diagnostic 24.7% (95%CI 19.5% to 29.9%), with subgroup analysis revealing rates of 34.4% (95%CI 22.0% to 40.5%) for post-fecal occult blood test and 26.6% (95%CI 22.6% to 30.5%) for primary colonoscopy screening. Diminutive conventional adenomas yielded a pooled rate of 59.9% (95%CI 43.4% to 76.3%). The pooled rate for overall serrated lesion detection was 12.4% (95%CI 8.8% to 16.0%). Male sex and higher age were significantly associated with an ADR above the benchmark.This first meta-analysis relying on real-world observational studies supports the ESGE benchmark for ADR, while suggesting that different benchmarks might be used according to indication, sex, and age.Thieme. All rights reserved.